Studies on the Biological Activity of Nicotinic Acid N-Oxide. IV

Tazaki, Hiroshi; Kanamitsu, Osamu

doi:10.1248/yakushi1947.81.12_1767

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1971

2009

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Cited by 6 publications

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“…Similarly, the vitamin B 6 derivative pyridoxine N-oxide (50) has been demonstrated to undergo reduction in yeast incubates 168 . Resting cells of Escherichia coli transform nicotinic acid N-oxide to nicotinic acid 169 ; it has been concluded that certain microbes can adaptively produce enzymes which reduce the N-oxide, so that the nicotinic acid formed can be utilized. Pyridylalanine N-oxides (51) block the growth of Escherichia coli, the 4-isomer being the most potent inhibitor 170 .…”

Section: Reductionsmentioning

confidence: 99%

N‐Oxidative Transformations ofCNGroups as Means of Toxification and Detoxification

Hlavica

Lehnerer

2009

Patai's Chemistry of Functional Groups

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Introduction Chemical Aspects of the N ‐Oxygenation of the C  N Functionality Occurrence of N ‐Oxygenated C  N Functionalities in Natural and Synthetic Compounds and Biological Activity Metabolic in Vivo and in Vitro Formation of N ‐Oxygenated C  N Functionalities Enzymology of the Formation of N ‐Oxygenated C  N Functionalities Further Transformations of N ‐Oxygenated C  N Functionalities Conclusions

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Section: Reductionsmentioning

confidence: 99%