Studies on the application of dynamic surface tensiometry of serum and cerebrospinal liquid for diagnostics and monitoring of treatment in patients who have rheumatic, neurological or oncological diseases

Kazakov, V. N.; Vozianov, Alexander; Sinyachenko, O.V.; Trukhin, Dmytro; Kovalchuk, V. I.; Pison, U.

doi:10.1016/s0001-8686(00)00031-2

Cited by 26 publications

(25 citation statements)

References 44 publications

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“…Several compelling examples of water stress as applied to humans can now be cited [26,37,38,44,45,[47][48][49][50][51][52][53][54][55][56][57]. Polycation-induced agglutination and sensitization of red blood cells has been demonstrated by several investigators [47][48][49][58][59][60][61][62][63][64][65][66][67].…”

Section: Introductionmentioning

confidence: 99%

“…Kratochvil and Hrncir demonstrated that the level of surface tension of the blood marks changes occurring in various disease conditions such as rheumatoid arthritis, proliferative glomerulonephritis, and some tumors of the central nervous system or the urogenital tracts [72]. Kazakov et al applied dynamic surface tensiometry of serum and cerebrospinal fluid for diagnosis and monitoring of treatment in patients with rheumatic, neurological and oncological diseases [57]. Esitashvili and Msuknishvili observed an increase in blood surface tension during acute myocardial infarction in humans [54].…”

Section: Introductionmentioning

confidence: 99%

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The Initial Common Pathway of Inflammation, Disease, and Sudden Death

Davidson¹,

Seneff²

2012

Entropy

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Abstract:In reviewing the literature pertaining to interfacial water, colloidal stability, and cell membrane function, we are led to propose that a cascade of events that begins with acute exogenous surfactant-induced interfacial water stress can explain the etiology of sudden death syndrome (SDS), as well as many other diseases associated with modern times. A systemic lowering of serum zeta potential mediated by exogenous cationic surfactant administration is the common underlying pathophysiology. The cascade leads to subsequent inflammation, serum sickness, thrombohemorrhagic phenomena, colloidal instability, and ultimately even death. We propose that a sufficient precondition for sudden death is lowered bioavailability of certain endogenous sterol sulfates, sulfated glycolipids, and sulfated glycosaminoglycans, which are essential in maintaining biological equipose, energy metabolism, membrane function, and thermodynamic stability in living organisms. Our literature review provides the basis for the presentation of a novel hypothesis as to the origin of endogenous bio-sulfates which involves energy transduction from sunlight. Our hypothesis is amply supported by a growing body of data showing that parenteral administration of substances that lower serum zeta potential results in kosmotropic cationic and/or chaotropic anionic interfacial water stress, and the resulting cascade.Keywords: inflammation; serum sickness; colloidal instability; interfacial water stress; bio-sulfates; Shwartzman phenomena; sudden death syndrome Glossary of TermsAnaphylaxis a severe, rapidly progressing, life-threatening, generalized allergic reaction. Biological equipoise a stable, non-equilibrium, dissipative system synonymous with life. Cholesterol sulfate (Ch-S)quantitatively the most important known sterol sulfate in human plasma where it regulates the activity of the serine proteases, in cell membranes where it has a stabilizing role, and in platelet membranes where it supports platelet adhesion. Coherence domain (CD)a water CD is a collection of liquid water molecules which oscillate in unison in tune with a self-trapped electromagnetic field at a well-defined frequency. The coherent oscillations produce an ensemble of quasi-free electrons, able to collect noise energy from the environment and transform it into high-grade coherent energy in the form of electron vortices. This high-grade energy may then activate biomolecules resonating with the water CD. Colloidal instabilitya property attributed to a colloidal suspension that develops when stabilizing repulsive steric and electrostatic forces between colliding particles are insufficient to prevent their natural tendency to aggregate into masses large enough to precipitate.Colloidal suspension a colloid that has a continuous liquid phase in which a solid is suspended in a liquid, e.g., our flowing blood. Exclusion zone (EZ)a glass-like, gel phase consisting of water CDs resonating in-phase, adjacent to hydrophilic surfaces, several hundred micrometers wide which excludes colloi...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Initial Common Pathway of Inflammation, Disease, and Sudden Death

Davidson¹,

Seneff²

2012

Entropy

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“…As a result, alveolar environment cannot be simulate closely, but for such model studies like these presented below, the fact that MBP method allows the discussion of measured phenomena with reference to the time scales characteristic for changes of alveolar surface during the breathing cycle is a sufficient requirement for application. What is more, according to [29,30] among all known methods, which can be used for measurements of dynamic surface tension in short time range, the maximum bubble pressure (MBP) method is the most appropriate one for medical applications involving biological liquids. What is important to add, dynamic surface tension of biologic liquids is essentially more sensitive to various pathologies than the corresponding equilibrium surface tension values [29][30][31].…”

Section: Dynamic Interfacial Tensiometry Of Pulmonary Surfactantmentioning

confidence: 99%

Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air–water interface

Kramek-Romanowska

Odziomek

Sosnowski

2015

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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“…Thus, the DST measurements of human biological liquids can be used for studies of various human disorders [6]. An interest in the fundamental and applied sides of such studies has been growing over recent years, as can be seen from the publications concerning the temperature dependence of blood surface tension [12], the main characteristics of the power spectrum of bubble oscillations for complex analysis [13], the analysis of tensiograms of cerebrospinal fluid [14,15], DST application as a medical diagnostic tool [16,17], etc.…”

Section: Introductionmentioning

confidence: 99%

Dynamic Surface Tension Measurements for Animal Blood Analysis and Correlations with Related Biochemical Parameters

Zaitsev

2018

Colloids and Interfaces

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Abstract:The dynamic surface tension (DST) data and biochemical parameters (BCP) of animal blood have been obtained. A strong positive correlation was found for goats between σ 1 , σ 2 , σ 3 (DST) and sodium levels (BCP), λ z (DST)-with the levels of lipid and sodium (BCP); whereas a strong negative correlation was found for goats between σ 3 (DST) and the level of total protein and chloride (BCP), λ z (DST)-with the level of albumin (BCP). A strong positive correlation was found for horses between σ 1 , σ 2 , σ 3 (DST) and lipid levels (BCP); λ 0 (DST)-the level of chloride (BCP); λ z (DST)-the level of albumin and chloride (BCP). A strong negative correlation was found for horses between σ 1 (DST) and sodium level (BCP); σ 2 , σ 3 (DST) and chloride level (BCP); λ 0 (DST) and lipid level (BCP). Some moderate and weak correlations of different types were also found, but these have less importance for practical usage. The particular correlations between BCP and DST data of the same serum samples allowed DST data to be checked directly at the farm, and requiring the use of more expensive and time-consuming biochemical analysis only in cases of high necessity for a particular animal.

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Studies on the application of dynamic surface tensiometry of serum and cerebrospinal liquid for diagnostics and monitoring of treatment in patients who have rheumatic, neurological or oncological diseases

Cited by 26 publications

References 44 publications

The Initial Common Pathway of Inflammation, Disease, and Sudden Death

The Initial Common Pathway of Inflammation, Disease, and Sudden Death

Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air–water interface

Dynamic Surface Tension Measurements for Animal Blood Analysis and Correlations with Related Biochemical Parameters

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