Studies on the antiinflammatory activity of Betula alnoides bark

Abstract

The antiinflammatory activity of Betula alnoides extract was evaluated in acute and subacute inflammation models. The extract was also evaluated for antiinflammatory activity in sheep RBC induced sensitivity and in membrane stabilization models. Except for the sheep RBC induced sensitivity model, the extract showed significant antiinflammatory activity.

Comparison of the Antiinflammatory Activities of Three Medicinal Plants Known as “Meiduoluomi” in Tibetan Folk Medicine

“…24,25) The presence of edema was chosen as the prime sign of in‰ammation in the current study based on the literature. 26) Xylene-induced mouse ear edema in the present study led to ‰uid accumulation and edema characteristic of the acute in‰ammatory response in the in vivo model. The methanolic extract of EM showed stronger antiphlogistic eŠects against xylene-induced mouse ear edema than that of EB, while AB was ineŠective in this model.…”

Ethanol extract from birch bark (Betula pubescens) suppresses human dendritic cell mediated Th1 responses and directs it towards a Th17 regulatory response in vitro

“…Among these effects are cytotoxicity [7], anti-oxidant [8], anti-viral (reviewed in [9]), anti-fungal [10], anti-cancer (reviewed in [11]), and anti-inflammatory activity (reviewed in [12]). Anti-inflammatory effects of extracts from the bark of B. alnoides have been shown in acute and subacute inflammation models in vivo [13] and extract from the bark of B. platyphylla was shown to reduce stiffness and histopathology score in collagenase-induced osteoarthritis in rats [14]. The triterpenes, lupeol and oleanolic acid, reduced chemically induced ear oedema in mice [15,16] and lupeol also inhibited production of prostaglandin E 2 (PGE 2 ) and inflammatory cytokines by macrophages in vitro [15].…”

Antioxidant properties of polyphenolic rich HPLC standardized extract of Beta vulgaris L. roots

“…Denaturation of proteins is responsible for the cause of inflammation is conditions like rheumatoid arthritis, diabetes, cancer etc. [17]. Mechanism of denaturation is involved in alteration of electrostatic force, hydrogen, hydrophobic and disulphide bonds.…”

“…The protein denaturation was assessed following the method of Sur et al (2003) [17]. In tubes, 0.05 ml of different concentrations of BR was added to 0.45 ml bovine serum albumin (5% aqueous solution).…”