1959
DOI: 10.1139/m59-048
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Studies on the Antigenic Structure of Trichinella Spiralis Larvae

Abstract: By means of physical and chemical procedures seven antigenic fractions have been isolated from Triclzinella spiralis larvae, a s determined by complement fisation. Some evidence is presented t o indicate that at least some of the isolated fractions are antigenically distinct and that antibodies in Triclzinella-infested rabbit develop a t different times for different fractions. Importance of using a properly selected antigen in serodiagnosis of trichinosis is discussed.'Manuscript

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Cited by 13 publications
(3 citation statements)
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“…Metabolites of certain nematodes have been shown to be immunogenic (Soulsby, 1958;Thorson, 1956;Ewert and Olson, 1960), to contain a variety of antigens , to have various enzymes (review: Soulsby, 1958), to induce shock in nematode-infected animals (Sprent, 1951 ) and in gut segments from nematodeinfected or metabolite-injected animals Olson, 1961, 1962), but in spite of some chemical characterization (review: Weinstein, 1959), little is known of metabolites in terms of allergenicity. Extracts of adult or larval nematodes have been shown to contain a variety of antigens (Wodehouse, 1956;Kagan, 1957;Labzoffsky et al, 1959; al., Tanner and Gregory, 1961;Huntley and Moreland, 1963). some of which induce anaphylaxsis in nematode-infected guinea pigs (Oliver-Gonzalez, 1946;Sprent, 1951;.…”
Section: Literature Reviewmentioning
confidence: 99%
“…Metabolites of certain nematodes have been shown to be immunogenic (Soulsby, 1958;Thorson, 1956;Ewert and Olson, 1960), to contain a variety of antigens , to have various enzymes (review: Soulsby, 1958), to induce shock in nematode-infected animals (Sprent, 1951 ) and in gut segments from nematodeinfected or metabolite-injected animals Olson, 1961, 1962), but in spite of some chemical characterization (review: Weinstein, 1959), little is known of metabolites in terms of allergenicity. Extracts of adult or larval nematodes have been shown to contain a variety of antigens (Wodehouse, 1956;Kagan, 1957;Labzoffsky et al, 1959; al., Tanner and Gregory, 1961;Huntley and Moreland, 1963). some of which induce anaphylaxsis in nematode-infected guinea pigs (Oliver-Gonzalez, 1946;Sprent, 1951;.…”
Section: Literature Reviewmentioning
confidence: 99%
“…Type 1 virus was isolated in Denmark (30), England (31), and Japan (32). Type 2 virus was recovered in England (33), Panama (34), and Canada (23), while type 3 virus was recognized in France (35), England (36), Canada (37), and Australia (38).…”
Section: Problem Of Etiologic Associationmentioning
confidence: 99%
“…Type 1 virus was isolated in Denmark (30), England (31), and Japan (32). Type 2 virus was recovered in England (33), Panama (34), and Canada (23), while type 3 virus was recognized in France (35), England (36), Canada (37), and Australia (38).…”
Section: Problem Of Etiologic Associationmentioning
confidence: 99%