Studies on Peroxovanadates. I. The Crystal Structure of Ammonium mu-Oxo-bis(oxodiperoxovanadate(V)), (NH4)4[O(VO(O2)2)2].

Svensson, Ing-Britt; Stomberg, Rolf; Rømming, Chr.; Lindberg, Annelie; Lagerlund, Inger; Ehrenberg, L.

doi:10.3891/acta.chem.scand.25-0898

Cited by 42 publications

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“…Early work focused on two areas. X-ray structure studies were concerned with defining the nuances of the coordination of hydrogen peroxide. − Other work concentrated on attempting to understand the mechanism of vanadate-catalyzed oxidation of halides , and the associated disproportionation of hydrogen peroxide into oxygen and water. , …”

Section: Introductionmentioning

confidence: 99%

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

et al. 1996

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A crystalline glycylglycine complex of monoperoxovanadate has been obtained and its X-ray structure determined. The coordination is pentagonal bipyramidal with the peroxo group and a tridentate glycylglycine occupying the equatorial positions. The axial positions of the anion are occupied by the oxo ligand and by one oxygen of the peroxo group of the adjacent anion. The latter interaction establishes the seventh bond and produces a dimeric structure in the crystalline material. NMR studies of its dissolution in water combined with previously reported results from equilibrium measurements show that the dimer dissociates in water to the monomeric precursor. It is proposed that this monomer corresponds to the complex responsible for the inhibition of the vanadium-catalyzed decomposition of hydrogen peroxide by glycylglycine. Crystal structure of [NEt(4)][VO(O(2))(GlyGly)].1.58H(2)O: monoclinic, space group P2(1); Z = 4; a = 10.618(2) Å; b = 14.803(2) Å; c = 11.809(2) Å; beta = 101.37(2) degrees; V = 1819.7 Å(3); T = 198 K; R(F)() = 0.029 for 2664 data (I(o) >/= 2.5sigma(I(o))) and 431 variables.

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Section: Introductionmentioning

confidence: 99%

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

et al. 1996

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“…4B). The reason for the higher sensitivity to catalase of PMo is uncertain, but in crystals, the MoOO peroxo bonds are 0.1 Å longer than the VOO peroxo bonds (25). There may, therefore, be less steric hindrance involved in catalase approaching the peroxo-groups in PMo.…”

Section: Spontaneous Breakdown and Inactivation By Exogenous Catalasementioning

confidence: 98%

“…Both diperoxovanadate and monoperoxovanadate are assumed to possess a seven-coordinated pentagonal bipyramidal geometry (25,38,39). Because of the reactivity of the peroxo group with thiols, we had expected the monoperoxovanadate to have a considerable biological activity.…”

Section: Thiol-induced Inactivation Of Pv and Pmo: Mathematical Modelmentioning

confidence: 99%

Properties of Pervanadate and Permolybdate

Mikalsen¹,

Kaalhus²

1998

Journal of Biological Chemistry

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Pervanadate and permolybdate are irreversible protein-tyrosine phosphatase inhibitors, with IC 50 values of 0.3 and 20 M, respectively, in intact cells. Maximal inhibition was obtained within 1 min at higher concentrations of the compounds. They induced prominent changes in the phosphorylation status of the gap junction protein, connexin43. These effects were utilized as model systems to assess the stability and inactivation of the compounds. Although the concentrated stock solutions were relatively stable, the diluted compounds were unstable. The biological activity had decreased to 20 -30% after 6 h of incubation in a phosphate buffer, 1 h in phosphate buffer with 10% fetal calf serum, and 1-3 minutes in culture medium. Thiols reacted rapidly with the compounds and inactivated them (initial reaction rates with cysteine: permolybdate > pervanadate > H 2 O 2 ). Catalase inactivated the compounds, and permolybdate was the more sensitive. The cells inactivated permolybdate faster than pervanadate. Cellular inactivation of permolybdate, and to a lesser degree pervanadate, appeared to be partly dependent on catalase and thiols. However, a general decrease in cellular thiols was not the mediator of the biological effects of pervanadate or permolybdate. Mathematical modeling of the thiol reactivity suggested that monoperoxovanadate at maximum could possess 20% of the biological activity of diperoxovanadate.

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“…Packing diagram of (IÁCa), with displacement ellipsoids drawn at the 50% probability level. (Svensson et al, 1971), in which V atoms are triply bridged by two peroxo groups and one oxo group, by removing the bridging oxo group to give positions for the coordination of the glycine ligand. The moiety is also related to [V 4 O 4 (O 2 ) 8 (PO 4 )] 7À (Schwendt et al, 1996) and [V 2 O 2 (O 2 ) 4 (PO 4 )] 5À (Schwendt et al, 1994), having so-called Ishii-Venturello and lacunary Ishii-Venturello-type structures, respectively, in which two V atoms are doubly bridged by two 1 , 2 -peroxo groups.…”

Section: Figurementioning

confidence: 99%

Calcium and strontium salts of (glycinato-κ²N,O)oxidobis(peroxido-κ²O,O′)vanadate(V) tetrahydrate

2013

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The title salts calcium (glycinato-κ(2)N,O)oxidobis(peroxido-κ(2)O,O')vanadate(V) tetrahydrate, Ca[VO(O2)2(NH2CH2COO)]·4H2O, and strontium (glycinato-κ(2)N,O)oxidobis(peroxido-κ(2)O,O')vanadate(V) tetrahydrate, Sr[VO(O2)2(NH2CH2COO)]·4H2O, crystallized at pH ca 7.4 with similar lattice parameters. The glycinate anion acts as a bidentate N,O-chelating ligand, and the V atom has a pentagonal bipyramidal geometry, with two η(2)-peroxo groups and the glycinate N atom in the equatorial plane, and one terminal oxo and a glycinate O atom at the axial positions. The H atoms of three of the four water molecules in the strontium salt exhibited disorder over three positions for each molecule.

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Studies on Peroxovanadates. I. The Crystal Structure of Ammonium mu-Oxo-bis(oxodiperoxovanadate(V)), (NH4)4[O(VO(O2)2)2].

Cited by 42 publications

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A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

Properties of Pervanadate and Permolybdate

Calcium and strontium salts of (glycinato-κ²N,O)oxidobis(peroxido-κ²O,O′)vanadate(V) tetrahydrate

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Studies on Peroxovanadates. I. The Crystal Structure of Ammonium mu-Oxo-bis(oxodiperoxovanadate(V)), (NH4)4[O(VO(O2)2)2].

Cited by 42 publications

References 0 publications

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ3N2,NN,O1)oxoperoxovanadate(V) Anion

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ3N2,NN,O1)oxoperoxovanadate(V) Anion

Properties of Pervanadate and Permolybdate

Calcium and strontium salts of (glycinato-κ2N,O)oxidobis(peroxido-κ2O,O′)vanadate(V) tetrahydrate

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A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

A Product Formed from Glycylglycine in the Presence of Vanadate and Hydrogen Peroxide: The (Glycylde-N-hydroglycinato-κ³N²,N^N,O¹)oxoperoxovanadate(V) Anion

Calcium and strontium salts of (glycinato-κ²N,O)oxidobis(peroxido-κ²O,O′)vanadate(V) tetrahydrate