Studies on Pancreatitis

Pancreatitis

“…It is doubtful if these procedures contribute any more useful information than can be obtained from a good history and more simple biochemical techniques. (6)The same may be said of the Intravenous Secretin test. The range of volume and of bicarbonate content of pancreatic secretions obtained by duodenal aspiration from normal subjects overlaps to a considerable degree with that found in patients with chronic pancreatitis (Saint and Weiden, 1953). …”

“…After a number of years the supervention of wasting or diarrhoea, or the discovery of glycosuria indicates the true nature of the disorder. Recurrent mild pancreatitis leading to fibrosis may be a complication of that rare familial disorder hypercholesterolaemia (Klatskin and Gordon, 1952; Comfort and Steinberg, 1952) or of cholelithiasis (Saint and Weiden, 1953). Attacks of pancreatitis may continue to occur after calculi have been removed in patients with cholelithiasis, indicating that other causes of recurring necrosis than regurgitation of bile, such as ischaemia due to arteriosclerosis of the pancreatic vessels, must be postulated.…”

Gastroenterology in Australia, 1949-69

“…Over approximately the same period Saint made careful clinical studies of two groups of patients with acute pancreatitis (Saint & Weiden, 1953;Saint, 1954). The importance of his and Joske's contributions lay in their recognition of the multiple aetiologies of this disease.…”