Studies on Non‐Thiazolidinedione Antidiabetic Agents. Part 2. Novel Oxyiminoalkanoic Acid Derivatives as Potent Glucose and Lipid Lowering Agents.

Abstract

acid derivatives, such as (VII), (IX) and (XII) are prepared by different approaches as depicted in the scheme. (IX) shows marked glucose and lipid-lowering activity without significant body-weight gain. -(IMOTO*, H.; SUGIYAMA, Y.; KIMURA, H.; MOMOSE, Y.; Chem. Pharm. Bull. 51 (2003) 2, 138-151; Pharm. Res. Div., Takeda Chem.