“…In humans, several cases of microfilariae detection in spleen, liver, bone marrow, lymph node, bronchial and kidney aspirates have been described (Vij et al , 2011; Vankalakunti et al , 2011; Varghese et al , 1996). The repartition of L. sigmodontis microfilariae in BALB/c mice is close to the one described previously for Sigmodon hispidus , the natural host of L. sigmodontis (Haas et al, 1981; Wenk, 1986; Wenk et al, 1979; Wenk et al, 1982). However, Wenk’s group reported almost no detection of microfilariae in the spleen of the jird, neither after intravenous inoculation nor during patency This difference can be due to technical approaches: in our study, microfilariae are detected by their DNA content, and thus dead or dying Mfs can be detected; furthermore, different susceptibilities of the hosts used for the experiment may influence detection.…”