Studies of positron range in tissue-equivalent materials

Minimization of parallax error in positron emission tomography using depth of interaction capable detectors: methods and apparatus

“…Since coincidence detection is related to the location of annihilation and not to the location of positron emission, there is an uncertainty in the localization of the true position of positron emission, resulting in the degradation of SR This contribution to the overall SR is determined from the FWHM of the positron count distribution, whose mean value is ≈0.6 mm for 18 F in water [15,16]. Experimental data indicates that positron range in different tissue-equivalent materials has a strong effect on SR [17]. The positron range of some standard and non-standard PET radionuclides has been characterized through imaging of small-animal quality control phantoms on a benchmark preclinical PET scanner, showing that the degradation of small animal PET resolution and quantitative accuracy correlates with increasing positron energy [18].…”