Studies of Acetal Phospholipides of Brain

Thannhauser, S. J.; Boncoddo, Nicholas F.; Schmidt, Gerhard

doi:10.1016/s0021-9258(18)56185-8

Cited by 43 publications

(2 citation statements)

References 5 publications

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“…The form of the crystals tvas identical with that reported for the natural compound. 7 The mixture was allowed to stand at room temperature until the crystallization was complete. The crystals were collected with suction on a buchner funnel, washed with 20 ml.…”

Section: Phosphorylation (mentioning

confidence: 99%

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The Synthesis of O-(L-α-Glycerylphosphoryl)-ethanolamine and Some Comments on the Stereochemical Aspects of the Biosynthesis of Glycerolphosphatides from Carbohydrates

Baer¹,

Stancer²

1953

J. Am. Chem. Soc.

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Section: Phosphorylation (mentioning

confidence: 99%

“…(41) Thannhauser, Boncoddo and Schmidt (7) report that a-GPE obtained by catalytic hydrolysis of beef brain plasmalogen sinters at 88°and melts at 155°. A gift of the natural -GPE from Professor Thannhauser and Dr. Schmidt permitted us to make simultaneous determinations of the melting points (40) of the natural and synthetic materials.…”

Section: Appendixmentioning

confidence: 99%

The Synthesis of O-(L-α-Glycerylphosphoryl)-ethanolamine and Some Comments on the Stereochemical Aspects of the Biosynthesis of Glycerolphosphatides from Carbohydrates

Baer¹,

Stancer²

1953

J. Am. Chem. Soc.

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A new histochemical technique for lipides applied to plasmal

Hack

1952

Anat. Rec.

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Almost since its introduction by Feulgen and Voit in 1924 the plasmal reaction has been enveloped by an aura of controversy. A large part of the disparities reported seems to stem from efforts to improve on the original method by the use of a variety of fixatives. It is our purpose to describe a procedure for preparing tissues for sectioning which preserves the original disposition of lipides and at the same time yields histological preparations of superior cytological detail. The description of the technique is followed by a report of its use in the study of the normal distribution of plasmalogens in a variety of tissues. These observations are in accord with those based on fresh frozen sections, as in the original Feulgen-Voit technique. Finally a comparison is made with formalin fixed material in an effort to resolve certain discrepancies in the literature.Plasmalogens are generally described as phosphatides of the lecithin-cephalin type whose two fatty acids are replaced by a single aldehyde (plasmal) of similar chain length. This aldehyde is linked to glycerol by an acetal bond; it is the special reactivity of this bond upon which the plasmal reaction depends, namely hydrolysis in acid solution catalyzed by HgCl,, freeing the carbonyl group for reaction with fuchsin sulfurous acid to produce an insoluble purple complex.

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Plasmalogens and Related Derivatives: Their Chemistry and Metabolism

Piantadosi

Snyder

1970

Journal of Pharmaceutical Sciences

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Studies of Acetal Phospholipides of Brain

Cited by 43 publications

References 5 publications

The Synthesis of O-(L-α-Glycerylphosphoryl)-ethanolamine and Some Comments on the Stereochemical Aspects of the Biosynthesis of Glycerolphosphatides from Carbohydrates

The Synthesis of O-(L-α-Glycerylphosphoryl)-ethanolamine and Some Comments on the Stereochemical Aspects of the Biosynthesis of Glycerolphosphatides from Carbohydrates

A new histochemical technique for lipides applied to plasmal

Plasmalogens and Related Derivatives: Their Chemistry and Metabolism

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