Studies in oral leukoplakia: A preliminary report on the period pervalence of malignant transformation in leukoplakia based on a follow-up study of 248 patients

Jj, Pindborg; Jolst, O; Renstrup, Grete; Roed‐Petersen, B.

doi:10.14219/jada.archive.1968.0127

Cited by 222 publications

(108 citation statements)

References 3 publications

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“…the two districts. Since different habit groups are known to differ in their age-distribution (Mehta et al, 1971) (Pindborg et al, 1968;Mehta et al, 1972). The regression of leucoplakia in the present material has been discussed by Mehta and Pindborg (1974 between the successive examinations.…”

Section: Methodsmentioning

confidence: 99%

Incidence of oral leucoplakias among 20,358 Indian villagers in a 7-year period

Mehta¹,

Pindborg²,

Bhonsle³

et al. 1976

Br J Cancer

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Summary.-A group of 20,358 villagers in two districts of India has been followed for 7 years to study the incidence of oral leucoplakia. The follow-up rate of the population in the two districts ranged from 610% to 710%. In one of the districts (Bhavnagar) no new cases of leucoplakia were found among females in the 7-year period. Among males 105 cases developed (4.0/1000/year). The incidence was highest among hookli (clay pipe) smokers. In the Ernakulam district the incidence among males was 3-3/1000/year whereas among females it was 19/1000/year. The mixed habits group had the highest incidence of oral leucoplakias (7.2 and 9-9/1000/ year among males and females respectively).HAVING established a register of oral precancerous lesions in two districts of India, Bhavnagar and Ernakulam, amongst 20,358 Indian villagers, these individuals were further followed up for a period of 7 years in order to study the incidence of new oral leucoplakia. Until now no incidence rates for oral leucoplakia have been reported.

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Section: Methodsmentioning

confidence: 99%

Incidence of oral leucoplakias among 20,358 Indian villagers in a 7-year period

Mehta¹,

Pindborg²,

Bhonsle³

et al. 1976

Br J Cancer

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“…[7][8][9] Although the potential for malignant transformation is higher in erythroplakia, speckled leukoplakia should not be neglected, since the red patches in this lesion have a similar histology to homogeneous erythroplakia. [10][11][12][13] The purpose of this study was to conduct a retrospective analysis of the clinical and pathological features of 13 cases of oral erythroplakia and speckled leukoplakia; the patients were seen at a clinic that specializes in stomatology and the histopathological diagnosis of mouth diseases.…”

Section: Introductionmentioning

confidence: 99%

Eritroplasia e leucoeritroplasia oral: análise retrospectiva de 13 casos

Hosni

Salum

Cherubini

et al. 2009

Rev. Bras. Otorrinolaringol.

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Eritroplasia e leucoeritroplasia são lesões orais cancerizáveis com elevado potencial de transformação maligna. OBJETIVOS: Neste estudo retrospectivo foram analisadas as características clínico-patológicas de 13 casos de eritroplasias e leucoeritroplasias orais de pacientes atendidos em um Serviço especializado em Estomatologia e diagnóstico histopatológico. MATERIAL E MÉTODO: Foram revisados os registros de biópsia de pacientes atendidos entre os anos de 1978 e 2006. Foram registradas e características clínicas e histopatológicas das lesões, bem como sexo, idade dos pacientes e associação com fatores de risco. RESULTADOS: As lesões exibiram predileção por pacientes do sexo masculino na proporção de 1:3.3. A média etária dos indivíduos foi de 57 anos e o palato mole foi o sítio envolvido em 77% dos casos. Sintomatologia dolorosa foi relatada por 61,5% dos pacientes e associação com tabagismo e etilismo foi observada em 100% e em 46% dos casos, respectivamente. As lesões analisadas exibiam displasia epitelial e mais de 50% foram diagnosticadas como carcinoma in situ ou carcinoma invasivo. CONCLUSÕES: Apesar de apresentarem baixa prevalência, as eritroplasias homogêneas e as leucoplasias salpicadas exibem alterações epiteliais que vão de displasia epitelial a carcinoma invasivo, o que justifica sua inclusão entre as lesões bucais com maior potencial de malignização.

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“…Oralna leukoplakija klinički se klasificira kao homogena ili nehomogena (1) i jedan je od najčešćih potencijalno malignih poremećaja (2,3). Nehomogeni oblik ima bijelu bradavičastu, čvorastu, ulceriranu ili eritematoznu površinu i češće se pretvara u zloćudni negoli homogeni (1).…”

Section: Uvodunclassified

“…Oral leukoplakia, clinically classified as homogeneous or non-homogeneous (1), is one of the most common potentially malignant disorders (2,3). The non-homogeneous type presents a white surface with verrucous, nodular, ulcerated or erythematous features, all including a greater risk of malignant transformation than homogeneous types (1).…”

Section: Introductionmentioning

confidence: 99%