STUDIES ABOUT SYNTHESIS, CHARACTERIZATION, AND THE EFFECT OF 2-n-PROPYL-3-ETHYL-3-METHYL-1,4,2-BENZOXAZA-PHOSPHORINE-2-OXIDE ON GROWTH PARAMETERS AND CHLOROPHYLL CONTENT OF WHEAT

Abstract

This article presents the synthesis and characterization of a new phosphorus heterocycle, namely 2-n-propyl-3-ethyl-3-methyl-1,4,2-benzoxaza-phosphorine-2-oxide, by a Mannich-type reaction between npropyl-dichlorophosphine, methyl ethyl ketone, and o-aminophenol.Taking into consideration that chlorophyll contents in plants were revealed to have connection with nitrogen and phosphorus concentrations at early growth stage, and because the above-mentioned heterocyclic compound can be considered as a phosphonic analogous of naturally occuring α-aminoacids, it was expected to develop biological activity from it. That is the reason why 2-n-propyl-3-ethyl-3-methyl-1,4,2-benzoxaza-phosphorine-2-oxide was subjected for biological tests on wheat.The present study was also undertaken to investigate the interrelationship between chlorophyll content, dry matter, and other growth parameters of wheat, after treatment with different concentrations of 2-n-propyl-3-ethyl-3-methyl-1,4,2-benzoxaza-phosphorine-2-oxide.

Synthetic methods of cyclic α-aminophosphonic acids and their esters

“…Methyl mercaptoacetate was added to a stirred solution of the diethyl trifluoroacetimidoylphosphonate (145) …”