Struggling With Ischemia Reperfusion Injury

Kayıran, Oğuz; Uysal, Afşin; Cuzdan, Suat Sedat; Koçer, Uğur

doi:10.1097/scs.0b013e31803fdff7

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Also, vitamin E and iloprost (synthetic analog of prostacyclin PGI 2 ) combination demonstrated that they attenuate reperfusion injury more efficiently than their separate use, in skeletal muscle I/R injury model [68]. In addition to these, Kayiran et al [69] showed that combined usage of vitamins C, E, acetylcysteine, and prednisolone alleviated the results of ischemia and enhanced the flap survival on free radial forearm flap. There is a wide range use of substances in the literature to prevent I/R injury, but there is no single ideal drug that can overcome this damage; so, we think that the use of combined therapy is more successful in achieving impressive results.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Antioxidants on Ischemia-Reperfusion Injury in Flap Surgery

Bozkurt¹,

Sezgiç²,

Karakol³

et al. 2019

Antioxidants

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Flap surgery has wide use in plastic surgery in the closure of tissue defects. In spite of the major advances in plastic surgery in the past years, flap surgery is still associated with significant mortality. Ischemia-reperfusion (I/R) injury, which is a complex injury associated with flap blood flow, is one of the most important causes of flap failure. The main pathophysiology underneath I/R injury is associated with reactive oxygen species, which can be prevented by certain antioxidant applications. Antioxidants have been widely used in flap surgery and I/R injury previously. There have been a lot of articles showing positive effects of antioxidants on I/R injury. In this chapter, we focus the mechanism of I/R injury and how antioxidants can able to diminish the damage, moreover demonstrating the effect of certain antioxidants on I/R injury that has been investigated previously.

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Section: Discussionmentioning

confidence: 99%

The Effect of Antioxidants on Ischemia-Reperfusion Injury in Flap Surgery

Bozkurt¹,

Sezgiç²,

Karakol³

et al. 2019

Antioxidants

View full text Add to dashboard Cite

show abstract

“…The palatal periosteum and flap should be maintained for maximum blood supply to the segmented bone, which is the most important factor [72], so that the bone is not devitalized as a result of ischemia after the bone is detached from its blood supply [73]. The use of piezoelectric device contributes for precise control of the osteotomy to reduce trauma to the soft tissue.…”

Section: Second Stage Surgerymentioning

confidence: 99%

New perspectives in the treatment of the severe atrophic posterior maxilla: interpositional sandwich osteotomy combined with sinus floor grafting - a novel technique

Fahim

2024

JSM

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Purpose: Dental implant installation in the posterior maxilla depends fundamentally on the presence of an adequate bone quantity. Tooth loss in the posterior maxilla is followed by extensive loss of the alveolar ridge and increased maxillary sinus pneumatization that often makes implant installation difficult to achieve. Maxillary sinus floor augmentation is traditionally the common surgical technique to overcome this situation. When the deficiency in the vertical dimension relates more to severe ridge resorption, crestal ridge augmentation should also be considered. Posterior maxillary sandwich osteotomy combined with sinus augmentation, using inter–positional bone graft might be a viable option to address this problem. This study describes a successful implementation of this technique to solve a severe vertical osseous ridge defect under the sinus floor. Material and Methods: A two–stage lateral wall sinus floor augmentation combined with inter–positional sandwich osteotomy followed by the insertion of dental implants with adequate length and diameter was performed. Deproteinized natural bovine bone mineral (DBBM) covered by a resorbable collagen membrane were used. Rehabilitation of this area was completed by a standard prosthetic protocol. Results: As a result of completing the above procedure favourable bone mass and form was created to enable implant placement in positions that are optimal from a prosthetic and esthetic point of view in terms of reshaping the alveolar crest and normali- zing the interocclusal distance improving the crown–implant ratio. Conclusion: This case demonstrates a step–by–step illustration of an innovative technique for overcoming a vertical ridge defect combined with increased maxillary sinus pneumatization. It can be concluded that this novel technique is recommended to meet the dimensional requirements of bone augmentation both crestal and intrasinusal in severe atrophic posterior maxilla to achieve an improved alveolar plane, equalized crown–to–implant ratios, and a more favourable gingival shape.

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Struggling With Ischemia Reperfusion Injury

Cited by 2 publications

References 7 publications

The Effect of Antioxidants on Ischemia-Reperfusion Injury in Flap Surgery

The Effect of Antioxidants on Ischemia-Reperfusion Injury in Flap Surgery

New perspectives in the treatment of the severe atrophic posterior maxilla: interpositional sandwich osteotomy combined with sinus floor grafting - a novel technique

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