Structures of sesquiterpenes from Curcuma longa

Antinociceptive effects of purified Curcuma longa in mice

“…Volatile oils include d-α-phellandrene, dsabinene, cinol, borneol, zingiberene, and sesquiterpenes. 4 The rhizomes are also reported to contain four new polysaccharides-ukonans along with stigmasterole, β-sitosterole, cholesterol, and 2-hydroxymethyl anthraquinone. 5,6 Nutritional analysis showed that 100 g of turmeric contains 390 kcal, 10 g total fat, 3 g saturated fat, 0 mg cholesterol, 0.2 g calcium, 0.26 g phosphorous, 10 mg sodium, 2500 mg potassium, 47.5 mg iron, 0.9 mg thiamine, 0.19 mg riboflavin, 4.8 mg niacin, 50 mg ascorbic acid, 69.9 g total carbohydrates, 21 g dietary fiber, 3 g sugars, and 8 g protein.…”

Sesquiterpenoids from the Rhizomes of <i>Curcuma phaeocaulis</i> and Their Inhibitory Effects on LPS-Induced TLR4 Activation

“…This extract was progressively fractionated with EtOAc, n-BuOH, and H 2 O, and the EtOAc-soluble fraction was subjected to various chromatographic experiments, which allowed us to isolate new guaianetype (2, 6), and furanogermacrane-type (11) sesquiterpenoids, as well as twelve known compounds: procurcumenol (1), 14) procurcumadiol (3), 14) zedoarondiol (4), 15) phaeocaulisine E (5), 7) wenyujinin L (7), 16) phacadinane B (8), 17) curcumenolactone A (9), 6) curcumenolactone B (10), 6) zedoarofuran (12), 18) curcolonol (13), 8) 4α-hydroxy-8,12-epoxyeudesma-7,11-diene-1,6-dione (14), 19,20) and neolitacumone A (15) 21) (Fig. 1).…”

“…Compound 6 was obtained as a yellow syrup, and its molecular formula of C 14 7) but differed due to the absence of one methyl group and one hydroxy group. This conclusion was further supported by the HMBC correlations between H-6 and C-5, C-8, and C-11; between the other olefinic proton H-9 and C-1, C-7, and C-14; and between the ethyl group (H 2 -11, H 3 -12) and C-7.…”

Transannular Cyclization of (4<i>S</i>,5<i>S</i>)-Germacrone-4,5-epoxide under Basic Conditions to Yield Eudesmane-Type Sesquiterpenes

“…plants. [8][9][10][11][12] Guaiane and its related compounds are thought to be obtained from (4S,5S)-germacrone-4,5-epoxide (1) by T-A cyclization in Curcuma sp. plants.…”