Structure of nanodiamonds prepared by laser synthesis

Байдакова, М. В.; Kukushkina, Yu. A.; Ситникова, A. А.; Yagovkina, M. A.; Kirilenko, D. A.; Соколов, В. В.; Shestakov, M. S.; Vul, A. Ya.; Zousman, Boris; Levinson, Olga

doi:10.1134/s1063783413080027

Cited by 51 publications

(39 citation statements)

References 18 publications

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“…TEM and AFM images of nanoparticles showed that they were cuboidal in shape and the size of individual particle was on average 3-5 nm, which was in agreement with the XRD results (Figure 2a, b and c). Chemical properties; FTIR spectra collected from the bulk ND ( Figure 2d) revealed typical ND peaks at 1107 cm -1 , 1177 cm -1 and 1256 cm -1 , which are due to stretching vibration of a C-O group 56 . Low intensity peaks were observed at 1384 cm -1 and 1436 cm -1 , which are associated with the aceto-group and C-H (SP 3 ) bending vibration.…”

Section: Resultsmentioning

confidence: 99%

Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study

et al. 2016

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The toxicity of nanomaterials raises major concerns because of the impact that nanomaterials may have on health, which remains poorly understood. We need to explore the fate of individual nanoparticles in cells at nano and molecular levels to establish their safety. Conformational changes in secondary protein structures are one of the main indicators of impaired biological function, and hence, the ability to identify these changes at a nanoscale level offers unique insights into the nanotoxicity of materials. Here, we used nanoscale infrared spectroscopy and demonstrated for the first time that nanodiamond-induced alterations in both extra- and intracellular secondary protein structures lead to the formation of antiparallel β-sheet, β-turns, intermolecular β-sheet, and aggregation of proteins. These conformational changes of the protein structure may result in the loss of functionality of proteins and in turn lead to adverse effects.

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Section: Resultsmentioning

confidence: 99%

Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study

et al. 2016

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“…For this purpose, different hot acid mixtures were used: HF/HNO 3 [26], successive HCl and H 2 SO 4 /HNO 3 /HClO 4 [27], successive H 2 SO 4 / HNO 3 and HCl [33,42]. In addition to oxidation, an annealing of HPHT NDs carried out in melted KNO 3 at 560°C [43] was very efficient to produce rounded NDs as shown by TEM (Fig.…”

Section: Chemical Purification Methodsmentioning

confidence: 98%

“…2.1), using pulsed laser ablation [1][2][3] or by crushing of diamond bulk materials grown by HPHT or CVD synthesis (Sects. 2.2 and 2.3).…”

Section: Nanodiamonds From Different Originsmentioning

confidence: 99%

Nanodiamonds: From Synthesis and Purification to Deposition Techniques, Hybrids Fabrication and Applications

Arnault

2016

Carbon Nanoparticles and Nanostructures

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The present chapter summarizes the recent advances in the production and the purification methods of nanodiamonds. The different strategies for seeding and patterning of surfaces are detailed. First reports of hybrids based on nanodiamonds are included like core shell particles or decoration with carbon dots or metallic atoms. Finally, an overview of applications for composites and nanomedicine is provided.

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“…A number of characteristic stretching vibrational peaks of NDs at 1107 cm -1 , 1177 cm -1 and 1256 cm -1 , which corresponds to C-O groups were observed. The appearance of these peaks may be related to the presence of post-manufacturing residues attached to the surface; NDs was produced using laser assisted technique, where fatty acids such as stearic acids are used [40]. The use of fatty acids may result in the presence of carboxyl groups on the surface of nanoparticles and they may react with each other and form an anhydride group and water molecule.…”

Section: Chemical Characterisationmentioning

confidence: 99%

Nanotoxicity of nanodiamond in two and three dimensional liver models

Khanal

Hau

Kondyurin

et al. 2017

IJNT

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Among classes of nanoparticles developed as drug carriers and theranostics, nanodiamond (ND) has been gaining an increasing attention owing to its biocompatibility, easy functionalisation and chemical stability. Although biocompatibility studies on nanodiamond produced by detonation technique have been explored extensively, NDs produced by laser assisted technique are yet to be investigated. Here, we present comparative study on toxicity of NDs in 2D and 3D liver models. Results suggest toxicity occurs on the 2D model at higher concentrations of NDs after long term exposure. D. Khanal et al.However, cytotoxic effect was not observed in the case of the 3D model. In addition, alterations in nanomechanical properties of the cells after uptake of NDs were detected by a Lorentz contact resonance (LCR) spectroscopic study. Overall, the results indicate differences in the toxicity profile of NDs in 2D and 3D and long term toxicity studies on NDs produced by laser assisted technique must be done prior to any biomedical applications.

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Structure of nanodiamonds prepared by laser synthesis

Cited by 51 publications

References 18 publications

Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study

Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study

Nanodiamonds: From Synthesis and Purification to Deposition Techniques, Hybrids Fabrication and Applications

Nanotoxicity of nanodiamond in two and three dimensional liver models

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