Abstract:Microtentacles (McTNs) are thin projections found on circulating tumor cells (CTCs) that can be tens of micrometers long. They have been recognized as a potentially critical factor in metastasis due to their involvement in attachment of CTCs to secondary sites of metastasis. So far little structural characterization has been reported, other than that these projections are based on microtubules (MTs), unlike most other cell projections that are based on actin. Work published to date strongly suggests that stabi… Show more
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