2015
DOI: 10.1002/ffj.3249
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Structure–odour relationships reviewed in the postgenomic era

Abstract: This review reports on the knowledge about odourant–olfactory receptor interactions and their projection within the field of structure–odour relationships (SOR). We provide a list of agonists and odour spaces associated with deorphanized human olfactory receptors. The link between olfactory receptor responses, differential perception and subtleties within odour families is discussed. Copyright © 2015 John Wiley & Sons, Ltd.

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Cited by 51 publications
(54 citation statements)
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“…is aroma in wine has previously been associated with various short-and long-chain ester compounds. ese include isoamyl acetate [6], ethyl pentanoate [7], hexyl acetate [8,9], ethyl isobutyrate [10], methyl (E)-geranoate ((E)-3,7-dimethyl-2,6-octadienoic acid methyl ester) [9], ethyl octanoate [8], isoamyl octanoate [9], and butyl butyrate [11,12]. Ethyl (E,Z)-2,4-decadienoate is an essential ingredient of the typical aroma in pears and their products and has not been previously described in wine and grapes from the Vitis vinifera [13].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…is aroma in wine has previously been associated with various short-and long-chain ester compounds. ese include isoamyl acetate [6], ethyl pentanoate [7], hexyl acetate [8,9], ethyl isobutyrate [10], methyl (E)-geranoate ((E)-3,7-dimethyl-2,6-octadienoic acid methyl ester) [9], ethyl octanoate [8], isoamyl octanoate [9], and butyl butyrate [11,12]. Ethyl (E,Z)-2,4-decadienoate is an essential ingredient of the typical aroma in pears and their products and has not been previously described in wine and grapes from the Vitis vinifera [13].…”
Section: Introductionmentioning
confidence: 99%
“…e literature statements [7][8][9][10][11][12] that butyl butyrate, ethyl pentanoate, and hexyl acetate are associated with pear aroma could not be certified in this consumer survey [18]. Otherwise, a proportion of qualified panelists have recognised the hitherto neglected compounds-ethyl decanoate, ethyl dodecanoate, and ethyl hexanoate-as pear-like aromas [18].…”
Section: Introductionmentioning
confidence: 99%
“…La relation entre la sensibilité à certains odorants et notre patrimoine génétique est de plus en plus étudiée et démontre que nous sommes loin d'être tous égaux vis-à-vis des odeurs ! (de March et al, 2015). À l'instar de la couleur de nos yeux, de celle de nos cheveux ou de notre taille, les gènes de nos récepteurs olfactifs nous rendent unique.…”
Section: Resultsunclassified
“…However, it is now quite well acknowledged that structure-odor relationships are not bijective. Very different chemicals trigger a typical "camphor" smell, while a single molecule, the so-called "cat-ketone" odorant, elicit two totally different smells as a function of its concentration [4]. At best, such SOR rules are obtained for a very tiny fraction of the chemical space, emphasizing that they must be decomposed into sub-rules associated with given molecular topologies [5].…”
Section: Introductionmentioning
confidence: 99%