Abstract:Ginsenoside Rh 2 (Rh 2 ) is one of the most effective anticancer components extracted from red ginseng, but the poor solubility limits its clinical application. In this paper, ginsenoside Rh 2 was modified with maleimidocaproic acid or maleimidoundecanoic acid with functional groups at both ends. The structures of derivatives were determined by analysis of 1D and 2D nuclear magnetic resonance, Fourier transform infrared, and highresolution mass spectrometry. Antiproliferative cell experiments showed that Rh 2 … Show more
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