Structure Identification And Biological Evaluation Of Compounds Isolated From Polygonum Hydropiper

Xiao, Huafeng; Ravu, RR; Jacob, .; Khan, SI; Tekwani, BL; Khan, IA; Wang, W; Li, XC

doi:10.1055/s-0036-1578767

Cited by 4 publications

(3 citation statements)

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“…The activities was observed to be ranked in the following order: PHS acetone (IC50 1.59 mg/mL; R 2 0.8330) > PHL acetone (IC50 2.94 mg/mL; R 2 0.9244) > PHL ethanol (IC50 5.14 mg/mL; R 2 0.9102) > PHS ethanol (IC50 6.88 mg/mL; R 2 0.8126). 5.52 mg/mL; R 2 0.7588). All types of extracts of the stem showed higher FRAP activity than those of the leaves of P. hydropiper.…”

Section: Antioxidant Capacitymentioning

confidence: 95%

“…Screening of extracts for α-amylase inhibition was carried as previously described for the starch iodine assay [ 5 ]. In brief, the assay mixtures composed of 120 μL of 0.02 M sodium phosphate buffer (pH 6.9 containing 6 mM sodium chloride), 1.5 mL of porcine pancreatic α-amylase (PPA) solution (0.05 mg/2 mL H 2 O) and P. hydropiper extracts (sample from solvent–solvent extraction) at concentrations ranging from 0.46 to 15 mg/mL (w/v) were incubated at 37 °C for 10 min.…”

Section: Methodsmentioning

confidence: 99%

“…It is commonly grown annually in the wet areas and is recognized as a common weed which is native to Southeast Asia [4]. Morphologically, the stem is round; its length usually varies from 40 to 70 cm [5].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents of Polygonum hydropiper L.

Nasır

Khan

Rehman

et al. 2020

Plants

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Polygonum hydropiper L. is a traditionally used medicinal plant. The present study was designed to explore the α-amylase inhibitory, antioxidant, and antimicrobial activities of Polygonum hydropiper L. Polarity-based solvent extracts (n-hexane, acetone, chloroform, methanol, ethanol, and water) of Polygonum hydropiper leaves and stem were used. Antioxidant activity was assessed by free radical scavenging assay (FRAP) and 2,2-diphenylpicrylhydrazyl (DPPH) free radical scavenging activity methods. Quantitative phytochemical analyses suggested that the stem of Polygonum hydropiper L. contains higher levels of bioactive compounds than its leaves (p < 0.05). The results suggested that stem-derived extracts of Polygonum hydropiper L. are more active against bacterial species, including two Gram-positive and three Gram-negative strains. Moreover, our results showed that the bioactive compounds of Polygonum hydropiper L. significantly inhibit α-amylase activity. Finally, we reported the polarity-based solvent extracts of Polygonum hydropiper L. and revealed that the stem, rather than leaves, has a high antioxidant potential as measured by FRAP and DPPH assay with IC50 values of 1.38 and 1.59 mg/mL, respectively. It may also be deducted from the data that the Polygonum hydropiper L. could be a significant candidate, which should be subjected to further isolation and characterization, to be used as an antidiabetic, antimicrobial and antioxidant resource in many industries, like food, pharmaceuticals and cosmetics.

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Section: Antioxidant Capacitymentioning

confidence: 95%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents of Polygonum hydropiper L.

Nasır

Khan

Rehman

et al. 2020

Plants

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A New Lignan from Gymnotheca involucrata

Zhang

Chen

2022

Chem Nat Compd

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Survey of natural products reported by Asian research groups in 2016

Liu

2017

Journal of Asian Natural Products Research

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The new natural products reported in peer-reviewed articles in 2016 in journals with good reputations were reviewed and analyzed. The advances that Asian research groups made in the field of natural products chemistry in 2016 were summarized. Compounds with unique structural features and/or promising bioactivities originating from Asian natural sources were discussed based on structural classification.

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Structure Identification And Biological Evaluation Of Compounds Isolated From Polygonum Hydropiper

Cited by 4 publications

References 0 publications

Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents of Polygonum hydropiper L.

Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents of Polygonum hydropiper L.

A New Lignan from Gymnotheca involucrata

Survey of natural products reported by Asian research groups in 2016

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