Structure, Function, and Regulation of the Chalcone Synthase

Cr, Martin

doi:10.1016/s0074-7696(08)60770-6

Cited by 91 publications

(57 citation statements)

References 185 publications

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“…For example, a block of the signal f l o d in one pathway, caused by a sun mutation, may result in an increase of the signal flow in another pathway, resulting in the overexpression of CHS gene expression. It should be noted, however, that CHS gene expression can be induced by many other externa1 stimuli, such as light, wounding, or stress (Chappell and Hahlbrock, 1984;Kubasek et al, 1992;Martin, 1993), and a mutation that affects light signal transduction processes or that causes additional stress may result in higher CHS mRNA levels. Also, CHS gene expression is expressed as part of the plant defense response (Chappell and Hahlbrock, 1984;Lamb et al, 1989).…”

Section: Discussion Lsolation Of Sun Mutants By Using An In Vivo Selementioning

confidence: 99%

Sucrose control of phytochrome A signaling in Arabidopsis.

et al. 1997

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The expression of the Arabidopsis plastocyanin (PC) gene is developmentally controlled and regulated by light. During seedling development, PC gene expression is transiently induced, and this induction can be repressed by sucrose. In transgenic seedlings carrying a PC promoter-luciferase fusion gene, the luciferase-induced in vivo luminescence was similarly repressed by sucrose. From a mutagenized population of such transgenic seedlings, we selected for mutant seedlings that displayed a high luminescence leve1 when grown on a medium with 3% sucrose. This screening of mutants resulted in the isolation of several sucrose-uncoupled (sun) mutants showing reduced repression of luminescence by sucrose. Analysis of the sun mutants revealed that the accumulation of PC and chlorophyll a/b binding protein (CAB) mRNA was also sucrose uncoupled, although the extent of uncoupling varied. The effect of sucrose on far-red light high-irradiance responses was studied in wild-type, sunl, sun6, and sun7 seedlings. In wild-type seedlings, sucrose repressed the far-red light-induced cotyledon opening and inhibition of hypocotyl elongation. sun7 seedlings showed reduced repression of these responses. Sucrose also repressed the far-red light-induced block of greening in wild-type seedlings, and both sun6 and sun7 were affected in this response. The results provide evidence for a close interaction between sucrose and light signaling pathways. Moreover, the sun6 and sun7 mutants genetically identify separate branches of phytochrome A-dependent signal transduction pathways.

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Section: Discussion Lsolation Of Sun Mutants By Using An In Vivo Selementioning

confidence: 99%

Sucrose control of phytochrome A signaling in Arabidopsis.

et al. 1997

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“…These repeats have also been found near the TATA box of other genes of the flavonoid pathway (Martin, 1993).…”

Section: Introductionmentioning

confidence: 89%

“…The H box is usually linked closely to the G-box domain, which appears to work in combination to elicit floral pigmentation in Antirrhinum and Phaseolus (Faktor et al, 1996). Box II is also known as the G-box, and its core motif (ACGT) is bound by a number of transcription factors that are associated with promoters other than the CHS promoter (Martin, 1993).…”

Section: Introductionmentioning

confidence: 99%

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Comparative genomics of chalcone synthase and Myb genes in the grass family.

Oberholzer¹,

Durbin²,

Clegg³

2000

Genes Genet. Syst.

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Most plant genes occur as members of multigene families where new copies arise through duplication. Duplicate genes that do not confer an adaptive advantage to the plant are expected to rapidly erode into pseudogenes owing to the accumulation of transpositions, insertion/deletion mutations and nucleotide changes. Nonfunctional copies will drift to fixation within a few million years and ultimately erode beyond recognition. Duplicate genes that are retained over longer periods of evolutionary time must be positively selected based on some adaptive advantage conferred on the plant species. We explore the dynamics of the recruitment of new duplicate genes for chalcone synthase, the enzyme that catalyzes the first committed step of flavonoid biosynthesis, and for the myb family of transcriptional activators. Our analyses show that new chs genes are recruited into the genome of grasses at a rate of one new copy every 15 to 25 million years. In contrast, the myb gene family is much older and many duplicate copies appear to predate the separation of the angiosperm lineage from other seed plants. The general pattern suggests a rapid adaptive proliferation of new chs genes but a more ancient elaboration of regulatory gene functions. Our analyses also reveal accelerated rates of protein evolution following gene duplication and evidence is presented for interlocus exchange among duplicate gene loci.

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“…The two other residues (His and Asn) of the catalytic triad ( Fig. 7) that appear to be important in the decarboxylation of the malonyl substrate [31,90] were predicted from the alignment of FAE1 with 3-ketoacyl-ACP synthase [KASIII involved in the condensation of malonyl-in polyketide synthesis [90,93]. is involved in substrate specificity [95].…”

Section: Fatty Acid Elongase-3 Ketoacyl Coa Synthases (Fae-3kcss)mentioning

confidence: 99%

Characterization of Enzymes Involved in Fatty Acid Elongation

Paul¹

2007

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Structure, Function, and Regulation of the Chalcone Synthase

Cited by 91 publications

References 185 publications

Sucrose control of phytochrome A signaling in Arabidopsis.

Sucrose control of phytochrome A signaling in Arabidopsis.

Comparative genomics of chalcone synthase and Myb genes in the grass family.

Characterization of Enzymes Involved in Fatty Acid Elongation

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