Structure, Expression, and Evolution of the D. melanogaster DPKQDFMRF-Amide Neuropeptide Gene

Taghert, Paul H.; Schneider, Lynne E.; O’Brien, Martha A.

doi:10.1007/978-1-4899-3668-4_25

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…This new set ofcells isevident usingantibodies against substance P ( Nassel,Lundquist,Hoog. and Grimelius,199O), FMRFamide (White et al, 1986;Taghert et al, 1990), and gastrin/CCK (Nassel et al, 1988 ). This second set of cells begins to express immunoreactivity by 24 h after pupar- iation.…”

Section: Changes In Transmitter Expression During Metamorphosismentioning

confidence: 99%

“…1990). As with the biogenic amines, most of the cells in the adult that contain FMRFamide-related peptides correspond to neurons that persisted from the larval stage (White et al, 1986;Taghert et al, 1990).…”

Section: Pattern Of Neuronal Survival Through Metamorphosismentioning

confidence: 99%

“…These changes are evident in Figure 2 which follows the changes in a set of ventral neurosecretory cells during metamorphosis. These neurons react with a number of peptide antisera including those raised against FMRFamide (White et al, 1986;Taghert et al, 1990), Substance P (White and Valles, 1985). gastrin/cholecystokinin (CCK) (Nassel, Ohlsson, and Cantcra, 1988), and the small cardioactive peptide B ( SCPB) (J. W. Truman, unpublished).…”

Section: Conserved Cellsmentioning

confidence: 99%

“…Witten, unpublished). Thus far, the data for Drosophila show considerable stability in the pattern of immunostaining through metamorphosis (Valles and White, 1988;Budnik and White, 1988;Taghert et al, 1990). There is, however, at least one case in which a shift may occur.…”

Section: Changes In Transmitter Expression During Metamorphosismentioning

confidence: 99%

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Metamorphosis of the central nervous system of Drosophila

1990

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The study of the metamorphosis of the central nervous system of Drosophila focused on the ventral CNS. Many larval neurons are conserved through metamorphosis but they show pronounced remodeling of both central and peripheral processes. In general, transmitter expression appears to be conserved through metamorphosis but there are some examples of possible changes. Large numbers of new, adult-specific neurons are added to this basic complement of persisting larval cells. These cells are produced during larval life by embryonic neuroblasts that had persisted into the larval stage. These new neurons arrest their development soon after their birth but then mature into functional neurons during metamorphosis. Programmed cell death is also important for sculpting the adult CNS. One round of cell death occurs shortly after pupariation and a second one after the emergence of the adult fly.

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Section: Changes In Transmitter Expression During Metamorphosismentioning

confidence: 99%

Section: Pattern Of Neuronal Survival Through Metamorphosismentioning

confidence: 99%

Section: Conserved Cellsmentioning

confidence: 99%

Section: Changes In Transmitter Expression During Metamorphosismentioning

confidence: 99%

See 2 more Smart Citations

Metamorphosis of the central nervous system of Drosophila

1990

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Invertebrate Endocrinology

Landau

Biggers

Laufer

1997

Comprehensive Physiology

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The sections in this article are: Growth and Morphogenetic Factors Insects Crustaceans Molluscs Other Invertebrates Regenerative Factors Crustaceans Insects Cnidarians Platyhelminths Annelids Echinoderms Others Pigmentary Factors Crustaceans Insects Osmoregulatory Factors Factors that May Increase Osmotic Pressure Factors that May Decrease Osmotic Pressure Metabolic Factors Biogenic Amines JHs and Farnesylacetone Adipokinetic Hormones and RPCH Crustacean Hyperglycemic Hormones Other Metabolic Factors Reproductive Factors Flatworms, Nemertines, and Nematodes Molluscs Crustaceans Insects Other Arthropods Annelids Echinoderms Behavioral Factors In Vitro Studies In Vivo Studies Pheromones Summary

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Comparison of the Allatostatin Neuropeptide Precursors in the Distantly Related Cockroaches

Ding¹,

Donly²,

Tobe³

et al. 1995

European Journal of Biochemistry

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Allatostatins are a family of insect neuropeptides that inhibit -juvenile hormone binsynthesis by the corpora allata. We have characterized cDNA and gcnomic DNA sequences that specify a preproallatostatin precursor in the oviparous cockroach Peripluriefa an~rricarin. Comparison of this prccursor with that previously described [Donly, B. C., Ding, Q., Tobe, S. S. &L Bcndena, W. G. (1993) Proc,. Nut/ Accrd. Sci.USA 90, 8807-88 1 1 ] for the viviparous cockroach Diploptei-ci pzi~ic'tutii revealed several cc)tnnion fcalures. First, thc precursors are remarkably similar in size and the organization of thc peptides within the precursor is conserved. The separation of the peptides into groups by acidic domains within the precursor has been maintained. The F nmericcinu precursor contains 14 allatostatin-like peptideb thal contain the core C-terminal sequence (Tyr/Phe)-Xaa-Phe-Gly-(l,eu/llc)-NH,, as compared to the I). piirictutu prccursor, which contains 13. Five of the peptides are perfectly conscrvcd between the two species. The rcmiiinder, with one exception, contain amino acid suhstitutions in the N-terminal address porlion of thc pcptide.Several features of expression are also similar between these two species. In both, u singlc copy gene specifies a large allatostatin transcript of 5.0 kb in I? unit>ric:cuici and 9.2 kb in D. putrrldu. I n F! w w r icum, allatostatin transcripts appear to be produced by numerous cells in different IXgiOllS of the brain.Kqywnrds: allatostatin ; Diploptera; Periplanete; juvenile horrnone; inscct.Rcproduction and inctmiorphosis in most insect species arc controlled by quantitative changes in the biosynthesis and secrction of the sesquitcrpenoid juvenile hormone from the corpora allata 11, 21. The rate of juvenile hormone biosynthesis in differcnt insect species appears to he conlrollcd by stimulatory and inhibitory factors (allatotropins and allatostatins, respectively), which for the most part originate in the brain and are transportcd via nerves to the corpora allata [ 2 ] . The presence of inhibitory molecules originating from the brain was first demonstrated using the cockroach as a modcl system. Transection of the braincorpora rtllata connective nervi corporis allati in several cockroach species resulted in stimulation of the rates of juvenile hormone biosynthesis [ 31. Recent experiments in a cockroach system 141 also suggest that ovarian factors may act on the brain to stimulate juvenile hormone biosynthesis by the corpora allata either by activating release of an allatotropic factor or by limiting the releasc of allatostatins.The only allatotropin characterized to date is an u-amidiited 13-ami no-acid neuropeptidc isolated from brain of the moth IS, 161.Cockroaches display several rcproducti ve inodcs that range frnrn oviparity to ovoviviparity to viviparity 117, 1 XI. The more pi-imitive [ 191 oviparous species, I-! n~rtwricwtcc, has ovcrlapping and continuous ovarian cycles that appear to br accompanied by on/off switching of juvenile hornione biosynthesis by cells of the...

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Structure, Expression, and Evolution of the D. melanogaster DPKQDFMRF-Amide Neuropeptide Gene

Cited by 3 publications

References 19 publications

Metamorphosis of the central nervous system of Drosophila

Metamorphosis of the central nervous system of Drosophila

Invertebrate Endocrinology

Comparison of the Allatostatin Neuropeptide Precursors in the Distantly Related Cockroaches

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