Structure elucidation of cyclohexene (9Z)-octadec-9-enyl ethers isolated from the leaves of Uvaria cherrevensis (Annonaceae)

Abstract

cyclohexene (9Z)-octadec-9-enyl ethers isolated from the Structure elucidation of cyclohexene (9Z)-octadec-9-enyl ethers isolated from the leaves of Uvaria cherrevensis (Annonaceae) leaves of Uvaria cherrevensis (Annonaceae)

(R)-3-(8'-Hydroxyfarnesyl)-indole and other chemical constituents from the flowers of Anomianthus dulcis and their antimalarial and cytotoxic activities

“…The crude extract and some secondary metabolites from this plant showed antibacterial (Ubonopas et al 2014;Kadchumsang et al 2015), anticancer, anti-Herpes Simplex Virus I (Ubonopas et al 2014), antispasmodic, (Wiya et al 2018) and antioxidant activities (Kadchumsang et al 2015). Furthermore, previous investigations of plants from the Uvaria genus have found several types of secondary metabolites such as polyoxygenated cyclohexenes (Ho et al 2015;Okpekon et al 2015;Hsu et al 2016;Auranwiwat et al 2017;Awale et al 2017;Auranwiwat et al 2019a;Auranwiwat et al 2019b), flavonoids (Salae et al 2017;Auranwiwat et al 2018), alkaloids (Auranwiwat et al 2018), naphthalenes (Auranwiwat et al 2017;Salae et al 2017), xanthenes (Macabeo et al 2014) and lignan glycosides (Nguyen et al 2015). Some of these chemical constituents have shown significant bioactivities, including anticancer (Macabeo et al 2014;Ho et al 2015;Awale et al 2017), anti-inflammatory (Hsu et al 2016), antimalarial (Auranwiwat et al 2017;Salae et al 2017), antimicrobial (Okpekon et al 2015), antiglycation and antioxidant activities (Thomas and Essien 2018).…”

Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS)

“…Given the promise of OzID-MS for facilitating double-bond placement in lipids, it is somewhat surprising that this technique has rarely been used in natural products, with most examples being of compounds similar to fatty acids but with various head groups. − For example, it aided in the elucidation of double-bond locations in several bisresorcinol and hexadecenoylanthranilic acid isomers. , While it is not possible to replace the tools and value of NMR characterization, OzID-MS can serve as an orthogonal structure elucidation tool. Essentially, initiation of ozonolysis across a carbon–carbon double bond in a mass spectrometer provides valuable data that complement those derived from NMR experiments.…”