Structure characterization, antioxidant and hypoglycemic activity of an arabinogalactoglucan from Scutellaria baicalensis Georgi

Hui, Heping; Gao, Weijun

doi:10.1016/j.ijbiomac.2022.03.022

Cited by 5 publications

(3 citation statements)

References 38 publications

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“…These polysaccharides have been found to exhibit various beneficial properties, including antioxidant, antiviral, and immunomodulatory activities. Studies have shown that the polysaccharide content in different processed forms of Scutellaria baicalensis Georgi varies, with the lowest content at 5% in grey Scutellaria baicalensis Georgi and the highest at 12% in fried Scutellaria baicalensis Georgi ( 20 ). Additionally, the polysaccharide content in Scutellaria baicalensis Georgi from different regions or varieties within the same region can be significantly different, yet it is generally maintained between 5.26–13.21%.…”

Section: The Chemical Components Of Scutellaria Baicalensis...mentioning

confidence: 99%

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Guo,

Li,

Dou

et al. 2024

Front. Nutr.

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Scutellaria baicalensis Georgi is a medicinal herb with a rich history of use in traditional Chinese medicine. This review concentrates on the chemical constituents of Scutellaria baicalensis Georgi, with a particular emphasis on flavonoids such as baicalin, baicalein, and wogonin. Additionally, it examines the effects of probiotic fermentation on the plant’s chemical profile and pharmacological actions. Evidence suggests that probiotic fermentation markedly modifies the bioactive components of Scutellaria baicalensis Georgi, thereby augmenting its medicinal potency. The paper delves into the mechanisms by which the primary active constituents of Scutellaria baicalensis Georgi are altered during fermentation and how these changes influence its pharmacological properties. This review aims to lay a theoretical groundwork for the clinical utilization of Scutellaria baicalensis Georgi and the formulation of innovative therapeutic approaches.

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Section: The Chemical Components Of Scutellaria Baicalensis...mentioning

confidence: 99%

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Guo,

Li,

Dou

et al. 2024

Front. Nutr.

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show abstract

“…Flavonoids and their glycosides are the main active ingredients, which have diversified effects, such as anti-tumor, anti-inflammatory, anti-aging, liver protection, and antioxidant. [44][45][46][47][48] Park et al 49 measured the total phenolic content (TPC) and antioxidant activity of SBE from different solvents and found a positive correlation between TPC and oxygen radical absorbance capacity. Han et al 50 identified that the bioactive components in scutellaria baicalensis are baicalein, visidulin III, and baicalin by LC-MS combined with a bioassay, showing strong free radical 2,2 0 -azinobis-3-ethylbenzothiazoline-6-sulfonate (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity.…”

Section: Introductionmentioning

confidence: 99%

“…So far, more than 40 chemical components have been identified in scutellaria baicalensis. Flavonoids and their glycosides are the main active ingredients, which have diversified effects, such as anti‐tumor, anti‐inflammatory, anti‐aging, liver protection, and antioxidant 44–48 . Park et al 49 measured the total phenolic content (TPC) and antioxidant activity of SBE from different solvents and found a positive correlation between TPC and oxygen radical absorbance capacity.…”

Section: Introductionmentioning

confidence: 99%

Influence of scutellaria baicalensis extract on the thermo‐oxidative and composting stability of poly(butylene adipate‐co‐terephthalate)

Li,

Kong,

Zhang

et al. 2023

Vinyl Additive Technology

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Scutellaria baicalensis extract (SBE), as a natural phenolic antioxidant, was added to poly(butylene adipate‐co‐terephthalate) (PBAT) matrix. With the addition of SBE, both the short‐term and long‐term antioxidant activity of PBAT samples noticeably improved. The results showed that the oxidation onset temperature (OOT) value of the modified sample (PBAT‐SBE2.5 sample) is increased by 62°C versus neat PBAT. Compared with neat PBAT with decreased OOT value after 240 days of storage, the OOT values of modified samples showed no significant change after long‐term storage. The excellent antioxidant activity is attributed to the high total phenolic content in SBE, which provides significant free radical scavenging efficiency. Additionally, the introduction of SBE could effectively enhance the processing performance of the PBAT matrix, the melt flow rate of PBAT‐SBE2.5 increased by ca. 42.6%. Compared with neat PBAT, the addition of SBE has no obvious effect on the mechanical properties of the matrix, the tensile strength remains unchanged and the elongation at break of PBAT‐SBE2.5 retains 74%. Composting degradation experiment indicated that the SBE promoted the degradation of PBAT. Moreover, SBE could reduce the surface hydrophilic tendency of the film materials. All results reveal that SBE was a good natural multifunctional stabilizer for PBAT.Highlights SBE shows high total phenolic content and free radical scavenging activity. SBE improves the short‐term and long‐term antioxidant activity of PBAT. The addition of SBE promoted the degradation of PBAT films. SBE could effectively enhance the processing performance of the PBAT matrix.

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Process optimization and effect of different extraction methods on the characteristics and activities of Herba Patriniae polysaccharides: A correlation analysis

Hui,

Wang,

et al. 2024

Arabian Journal of Chemistry

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Structure characterization, antioxidant and hypoglycemic activity of an arabinogalactoglucan from Scutellaria baicalensis Georgi

Cited by 5 publications

References 38 publications

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Influence of scutellaria baicalensis extract on the thermo‐oxidative and composting stability of poly(butylene adipate‐co‐terephthalate)

Process optimization and effect of different extraction methods on the characteristics and activities of Herba Patriniae polysaccharides: A correlation analysis

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