Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba

Yuan, Fei; Yu, Rongmin; Yin, Yin; Shen, Jianru; Dong, Quanfeng; Zhong, Linda L. D.; Song, Liyan

doi:10.1016/j.ijbiomac.2010.02.002

Cited by 55 publications

(24 citation statements)

References 21 publications

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“…The 1631 cm −1 band was due to the bound water. The polysaccharide also appears to have a specific band between 1200 and 1000 cm −1 , which is dominated by ring vibrations overlapped with stretching vibrations of C O glycosidic band vibration [12][13][14][15][16][17]. A characteristic peak near 894 cm −1 was also found in PPS, indicating PPS was a ˇ-d-glucan.…”

Section: Isolation Purification Composition and Characterization Ofmentioning

confidence: 90%

Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata

Deng

et al. 2012

International Journal of Biological Macromolecules

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Section: Isolation Purification Composition and Characterization Ofmentioning

confidence: 90%

Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata

Deng

et al. 2012

International Journal of Biological Macromolecules

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“…[20] The concentrations of biosynthesis products on the selected cell lines were in the range of 0.0185-0.5000 μmol/ml.…”

Section: Methodsmentioning

confidence: 99%

Stereo and region-selective biosynthesis of two new dihydroartemisinic acid glycosides by suspension-cultured cells of Artemisia annua

Zhu

Zeng

Song³

et al. 2014

Phcog Mag

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Background:The system of plant-cultured cells is one of the optimal systems to investigate biosynthesis pathway and their bioactive intermediates.Objective:To study the biosynthesis of dihydroartemisinic acid (1) by suspension-cultured cells of Artemisia annua.Materials and Methods:Substrate (compound 1) was administered into the suspension-cultured cells of A. annua and co-cultured for 2 days. The methanol extract was separated on various column chromatography methods and the structures of two biosynthesis products were elucidated based on the analysis of 1H NMR, 13C NMR, 2D NMR, and ESI-MS. Time-course curve was also established. Furthermore, in vitro antitumor activities of compounds 1-3 against HepG2, K562, and A549 cell lines were evaluated by MTT assay.Results:Two new compounds were obtained, namely 3α-hydroxy-dihydroartemisinic acid-α-D-glucopyranosyl ester (2) and 15-hydroxy-cadin-4-en-12-oic acid-β-d-glucopyranosyl ester (3). The results demonstrated that the cultured cells of A. annua possessed the abilities to stereo-selective hydroxylate and region-selective glycosylate sesquiterpene compounds in a highly efficient manner. Inhibitory effects of compounds 1-3 on proliferation of HepG2, K562, and A549 cell lines in vitro were also investigated.Conclusion:Two new dihydroartemisinic acid glycosides were obtained by stereo- and region-selective biosynthesis with cultured cells of A. annua.

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“…DPPH radical-scavenging assay 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was measured using the method with slight modification (28). The solution of DPPH radical (0.1 mM) in methanol was prepared and 1.0 mL of this solution was added to 3.0 mL of the polysaccharide of different concentrations (0.1-3.2 mg/mL) in water.…”

Section: Determination Of Antioxidant Activities In Vitro Of Pepw80-1mentioning

confidence: 99%

Structural characterization and biological activities of a novel polysaccharide from <i>Phyllanthus emblica </i>

Zeng

Lv²,

Jing³

et al. 2017

DD&T

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Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba

Cited by 55 publications

References 21 publications

Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata

Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata

Stereo and region-selective biosynthesis of two new dihydroartemisinic acid glycosides by suspension-cultured cells of Artemisia annua

Structural characterization and biological activities of a novel polysaccharide from <i>Phyllanthus emblica </i>

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