Structure-Based Virtual Screening: Successes and Pitfalls
Adenilson Lima,
André Penteado,
Jullyane de Jesus
et al.
Abstract:Structure-based virtual screening (SBVS) is an important approach that makes the first stages of drug development and repurposing processes faster and more efficient. Advances in experimental techniques and in silico computational modeling have contributed significantly to the characterization of diverse biological targets. Combined with the rapidly growing number of chemical compounds available in virtual databases, these advances enable the effective application of SBVS for prioritization of putative bioacti… Show more
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