“…Bromodomain-containing proteins (BCPs) can decipher the acetylation code of proteins via binding to their acetylated lysine (KAc) residues, which further modulates acetylation signal transduction and produces diverse physiological functions [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ]. BCPs are divided into eight subfamilies containing the bromodomain and extra-terminal domain (BET) subfamily [ 11 , 12 ]. The BET subfamily [ 12 ] consists of BRD2 [ 13 ], BRD3 [ 14 ], BRD4 [ 12 , 15 ] and BRD testis-specific protein BRDT [ 16 , 17 ].…”