Structure, antioxidant and immunostimulatory activities of the polysaccharides from Sargassum carpophyllum

Perspective on the Therapeutic Applications of Algal Polysaccharides

“…Di et al [ 138 ] observed that crude polysaccharide procured from Gracilaria dura (formerly known as Gracilaria rubra ) exhibited immunostimulatory activity on RAW264.7 macrophages cell. Two polysaccharides designated as SCP1 and SCP2, isolated from Sargassum carpophyllum demonstrated immunostimulatory activity by promoting the secretion of cytokines, interleukin-2 (IL-2) and tumour necrosis factor-α (TNF-α) [ 164 ]. Recent studies have shown that Ulva australis (formerly known as Ulva pertusa ) polysaccharide promotes the proliferation and phagocytic activity of macrophage, release of nitric oxide, and secretion of TNF-α and IL-6 [ 165 ].…”

“…Although, polysaccharides from different algal species displayed strong antioxidant activities, the actual mechanism of action of polysaccharides demands a detailed investigation. Also, it is reported that the structural features of algal polysaccharides such as molecular weight, monosaccharide make-up, degree and position of sulphation [164,191,192], greatly influence the antioxidant activity, however, how these features affect the activity, is yet unclear.…”

Fluorescent “on–off–on” sensor based on N,S co-doped carbon dots from seaweed (Sargassum carpophyllum) for specific detection of Cr(vi) and ascorbic acid

“…CCK-8 analysis was carried out to evaluate the cytotoxicity of CD in vitro. 28 Briey, L929 cells with an average density of 3.0 Â 10 5 cells per mL were seeded in a 96-well microplate with complete medium. Aer 24 h of incubation (37 C, 5% CO 2 ), the fresh DMEM mediums containing serial concentrations of N,S-CDs (0-1000 mg mL À1 ) were added into the plate well.…”

Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression

“…Humans can obtain polysaccharides by ingesting the corresponding foods and obtain energy through a series of digestion and absorption, such as the starch in cereal foods, which is a critical source of energy ( Lovegrove et al, 2017 ). After scientists’ unremitting research, the antioxidant, anti-aging and immunity-regulating functions of polysaccharides have been widely used ( Tian et al, 2020 ; Ren et al, 2021 ). In addition to these well-known functions of polysaccharides, scientists have found that polysaccharides and intestinal microorganisms have an interactive relationship.…”

“…SCFAs, as the main metabolites of intestinal microorganisms, occupy a critical position in intestinal physiology (Ahmadi et al, 2017;Dupraz et al, 2021). After several years of research, the role of SCFAs has not only been limited to regulating the body's metabolism but also been found to play an essential role in gut-brain communication (van de Wouw et al, 2018;Silva et al, 2020).…”