Structure and Properties of Benzonaphthofurandione Derivatives

Synthesis of Benzo[b]naphtho[2,3-d]furan-6,11-dione via One-pot Remote Anionic Fries Rearrangement and Metalation Reaction

“…3 Recent interest in 2 is heightened by their particularly promising activity in several anticancer and anticoccidial W5599A tests. 4 Brazanquinones 2 have previously been obtained by complex reaction sequences in only moderate yields, [4][5][6][7][8][9] which cannot be of widespread use in the construction of brazanquinones substituted on ring A.…”

Heterocyclic Quinones from 2,3-Dichloro-1,4-naphthoquinone.

“…Dinaphthofurandiones 0 2,3-Dichloro-5-nitro-l,4-naphthoquinone has been condensed with m-methoxyphenol, in the presence of pyridine, to yield a mixture of 3-methoxy-7 (and 10)nitrobenzo [6 ] naphtho [2,3-d [furan-6,11-diones. Aminoand bromo-3 -methoxybenzo [5 [naphtho [2,3 -d ]furan-6,ll-diones have been prepared from the above nitro derivatives (74).…”

“…Direct nitration of 3-methoxybenzo [5 [naphtho [2,3d ]-furan-6,11-dione (XI) gives nitro derivatives with nitro groups in the benzene ring containing the methoxy group (44, 74).…”

Synthesis and Activity of BNF15 Against drug-resistant Mycobacterium Tuberculosis

“…Naphthoquinones have also been reported to possess diverse biological functions, including antibacterial and antifungal effects [14]. Coenzyme Q (benzoquinone derivative), a fat-soluble vitamin, has antioxidant properties [15]. Vitamin K (naphthoquinone derivative) is an important factor in blood clotting [10].…”