Structure and Hypotensive Effect of Flavonoid Glycosides in Kinkan (<i>Fortunella japonica</i>) Peelings

Kumamoto, Hiroyasu; Matsubara, Yoshiharu; Iizuka, Yoshitomi; Okamoto, Kozo; Yokoi, Katsumi

doi:10.1080/00021369.1985.10858531

Cited by 23 publications

(25 citation statements)

References 7 publications

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“…Eight flavonoid glycosides were isolated from Fortunella japonica peelings and some of these compounds were regarded as important constituents, having a depressive effect on blood pressure. Their structures were assigned to 6,8-di-C-glucosyl apigenin, 3,6-di-C-glucosyl acacetin, 2″-O-α-L-rhamnosyl-4′-O-methyl-vitexin, 2″-O-α-L-rhamnosyl-4′-O-methyl-isovitexin, 2″-O-α-L-rhamnosyl vitexin, 2″-O-α-L-rhamnosyl orientin, 2″-O-α-L-rhamnosyl-4′-O-methyl orientin and poncirin [4].…”

Section: Introductionmentioning

confidence: 99%

“…Fresh kumquat fruits can be eaten raw or they can be used in making liqueur, marmalade, jam and sauce; they can also be pickled or candied. The fruits and leaves of the Fortunella species have been used in folk medicine in China and recently more attempts have been made to study the pharmacological activities of some bioactive compounds isolated from kumquat [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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Polyphenolic Composition and Antioxidant Characteristics of Kumquat (Fortunella margarita) Peel Fractions

Sadek

Makris

Kefalas

2009

Plant Foods Hum Nutr

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The polyphenolic composition of two Fortunella margarita (Nagami kumquat) specimens from Greece and Egypt was investigated employing fractionation by solvent partition and liquid chromatography-mass spectrometry. The main groups of phenolics identified in the different fractions generated were C-glycosylated flavones, O-glycosylated flavones, C-glycosylated flavanones, O-glycosylated flavanones, flavonols, chalcones, phenolic acids and derivatives thereof. The antioxidant potency of the fractions was assessed using two representative in vitro tests, including antiradical activity and hydroxyl free radical scavenging activity. It was revealed that the ethyl acetate fractions from both specimens contained the higher polyphenol content and exhibited the better antioxidant characteristics. The results indicated that F. margarita peels may be regarded as a rich source of potentially bioactive polyphenols.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Polyphenolic Composition and Antioxidant Characteristics of Kumquat (Fortunella margarita) Peel Fractions

Sadek

Makris

Kefalas

2009

Plant Foods Hum Nutr

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“…These compounds have also been isolated from citrus species: lemon, unshiu, sudachi and yuzu (Kumamoto, 1985). In the last reference the importance of receiving such compounds through nutrition was mentioned.…”

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confidence: 98%

Analysis of antioxidant compounds in sweet orange peel by HPLC–diode array detection–electrospray ionization mass spectrometry

Anagnostopoulou¹,

Kefalas

Kokkalou³

et al. 2004

Biomedical Chromatography

136

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HPLC-diode array detection-electrospray ionization mass spectrometry was used to determine qualitatively and quantitatively the flavonoid content of several fractions and residues of extracts of Greek navel sweet orange peel (Citrus sinensis) from the region of southern Greece (Leonidi-Tripoli). The main groups of flavonoids found according to HPLC retention times, spectral data and literature references were polymethoxylated flavones, C-glycosylated flavones, O-glycosylated flavones, O-glycosylated flavanones, flavonols and phenolic acids and their derivatives. The ethyl acetate fraction which has been shown in previous work to possess the best radical scavenging activity among the others was found to contain C-glycosylated flavones, polymethoxylated flavones, O-glycosylated flavones, O-glycosylated flavanones, two phenolic acid derivatives and two unknown compounds, all in low concentrations. The group of C-glycosylated flavones was reported for the first time in the peel of Navel sweet orange. The C-glycosylated flavones found according to their spectral characteristics and literature were 6-C-beta-glucosyldiosmin, 6,8-di-C-glucopyranosylapigenin, 6,8-di-C-beta-glucosyldiosmin and two unknown. The results suggest that the ethyl acetate fraction of navel Citrus sinensis peel consists of significant antioxidant compounds and can be used as a food additive of natural origin or a pharmaceutical supplement using as a source of peel the byproducts of the orange juice industry.

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“…The amount of TBARS in the serum fraction of blood is expressed as malondialdehyde (nmol) 2 Activity was measured in the reaction mixture after adding NAD+ isorhamnetin-fed and rhamnetin-fed rats. The content of total liver cholesterol was significantly less in the rats fed with 0.1 % isorhamnetin, 0.2 % rhamnetin, and 0.2 % quercentin.…”

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confidence: 99%

Effects of Isorhamnetin, Rhamnetin, and Quercetin on the Concentrations of Cholesterol and Lipoperoxide in the Serum and Liver and on the Blood and Liver Antioxidative Enzyme Activities of Rats

Igarashi

Ohmuma

1995

Bioscience, Biotechnology, and Biochemistry

101

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Structure and Hypotensive Effect of Flavonoid Glycosides in Kinkan (Fortunella japonica) Peelings

Cited by 23 publications

References 7 publications

Polyphenolic Composition and Antioxidant Characteristics of Kumquat (Fortunella margarita) Peel Fractions

Polyphenolic Composition and Antioxidant Characteristics of Kumquat (Fortunella margarita) Peel Fractions

Analysis of antioxidant compounds in sweet orange peel by HPLC–diode array detection–electrospray ionization mass spectrometry

Effects of Isorhamnetin, Rhamnetin, and Quercetin on the Concentrations of Cholesterol and Lipoperoxide in the Serum and Liver and on the Blood and Liver Antioxidative Enzyme Activities of Rats

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