2021
DOI: 10.1101/2021.12.13.472342
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Structure and dynamics of human disease-complication network

Abstract: A complication is an unanticipated disease arisen following, induced by a disease, a treatment or a procedure. We compile the Human Disease-Complication Network from the medical data and investigate the characteristics of the network. It is observed that the modules of the network are dominated by the classes of diseases. The relations between modules are unveiled in detail. Three nontrivial motifs are identified from the network. We further simulate the dynamics of motifs with the Boolean dynamic model. Each … Show more

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“…Empirical studies in the last two decades on real-world complex networks such as collaboration, communication, social, biological, and temporal networks are assumed to follow a power law distribution [10], [13], [20]- [22]. Consequently, scale-free complex networks are recently used as an essential substrate for studying many other facts in network science, such as human interaction [23], [24], COVID-19 pandemic [25], [26], and information diffusion [27], [28] among many others.…”
Section: Introductionmentioning
confidence: 99%
“…Empirical studies in the last two decades on real-world complex networks such as collaboration, communication, social, biological, and temporal networks are assumed to follow a power law distribution [10], [13], [20]- [22]. Consequently, scale-free complex networks are recently used as an essential substrate for studying many other facts in network science, such as human interaction [23], [24], COVID-19 pandemic [25], [26], and information diffusion [27], [28] among many others.…”
Section: Introductionmentioning
confidence: 99%