Structure and Antimicrobial Activity of Diterpenes from the Roots of Plectranthus hereroensis

Batista, Olga; Duarte, Aida; Nascimento, Juarez Vieira do; Simões, M. Fátima; Torre, Marı́a C. de la; Rodrı́guez, Benjamı́n

doi:10.1021/np50108a031

Cited by 71 publications

(49 citation statements)

References 10 publications

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“…Many plants have been used because of their antimicrobial traits, which are due to compounds synthesized in the secondary metabolism of the plant, such as phenols, 41 essential oils, 42 terpenoids, 43,44 alkaloids, 24 and flavonoids. 45 …”

Section: Discussionmentioning

confidence: 99%

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Fullerton

Khatiwada

Johnson

et al. 2011

Journal of Medicinal Food

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The use of medicinal plants as natural antimicrobial agents is gaining popularity. Sorrel (Hibiscus sabdariffa) is widely used for the treatment of diseases. The objective of this study was to investigate the antimicrobial activity of sorrel on Escherichia coli O157:H7 isolates from food, veterinary, and clinical samples. Phenolics of the calyces were extracted from 10 g of ground, freeze-dried samples using 100 mL of 80% aqueous methanol. Concentrations of 10%, 5%, and 2.5% methanol extract of sorrel were investigated for its antimicrobial activity. Inhibition zones were indicated by a lack of microbial growth due to inhibitory concentrations of sorrel diffused into semisolid culture medium beneath the sorrelimpregnated disk. The results of this experiment showed that the most potent sorrel concentration was 10%, then 5%, and finally 2.5%. The overall mean zone of inhibition for the sorrel extract was 12.66 mm for 10%, 10.75 mm for 5%, and 8.9 mm for 2.5%. The highest inhibition zones (11.16 mm) were observed in veterinary samples, and the lowest (10.57 mm) in the food samples. There were significant (P < .05) differences among mean zones of inhibition found in the food, veterinary, and clinical sources. Based on the source of samples and concentration of sorrel extract, the lowest mean inhibition was 7.00 -0.04 mm from clinical samples, and the highest was 15.37 -0.61 mm from a food source. These findings indicated that sorrel was effective at all levels in inhibiting E. coli O157:H7; thus it possesses antimicrobial activity and hold great promise as an antimicrobial agent.

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Section: Discussionmentioning

confidence: 99%

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Fullerton

Khatiwada

Johnson

et al. 2011

Journal of Medicinal Food

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“…Similarly, da Silva et al (2008) have reported significant MIC values against many grampositive and gram-negative bacteria. Novel antibacterial actions of plant extracts or phytocompounds have been demonstrated, which include inhibition of the MDR-efflux pump (Dixon et al, 1983), -lactamase activity (Tsuchiya et al, 1994), anti-antibiotic resistance properties (Batista et al, 1994), and R-plasmid elimination (Borris, 1996). In our study, most ESL-positive strains resistant to several antibiotics were found to be sensitive to the plant extracts.…”

Section: Resultsmentioning

confidence: 58%

Activity ofEugenia jambolana, an ethnomedical plant, against drug-resistant bacteria

Jasmine¹,

Selvakumar²,

Daisy³

et al. 2010

Pharmaceutical Biology

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“…Uma triagem ("screening") de avaliação da atividade antifúngica de produtos naturais, em seu estado puro ou "in natura"é considerado como o ponto de partida laboratorial para a prospecção de vegetais com perfil de bioatividade potencial, proporcionando conhecimento sobre a segurança no uso dos mesmos (AFOLAYAN; MEYER, 1997, BATISTA et al, 1994.…”

Section: Descrições Resultados Interpretaçõesunclassified

Triagem in vitro de atividades antifúngica de óleos essenciais sobre leveduras de Candida como estratégia de prospecção e racionalização do uso de fitoterápicos

Melo¹,

Batista²,

Gurgel³

2017

RPI

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This article shows the antifungal properties of eight essential oils extracted of plants widely known by the Brazilian popular knowledge. This is a prospective experimental study and for its execution, it was done a qualitative antibiogram with ten strains of Candida spp and essential oils. The inhibition zones varied among 9,4mm to 24,9mm. This study demonstrates the importance of efficient and accessible therapies as an alternative to the unreasonable use of synthetic medicines. KEYWORDS: Phytotherapy; Candida; essential oils; EL ENSAYO IN VITRO DE ACTIVIDAD ANTIFÚNGICA DE ACEITES ESENCIALES SOBRE LEVADURAS DE CANDIDA COMO ESTRATEGIA DE PROSPECCIÓN Y RACIONALIZACIÓN DEL USO DE FITOTERÁPICOS RESUMENEste artículo pretende evidenciar las propiedades antifúngicas de ocho aceites esenciales extraídos de las plantas, siendo estas ampliamente conocidas por el saber popular brasileño. Esta investigación es de carácter experimental con realización de antibiograma con cepas de Candida spp y aceites esenciales. Esta investigación muestra la importancia de terapias eficaces y accesibles como una alternativa frente al uso indiscriminado de medicamentos sintéticos.

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Structure and Antimicrobial Activity of Diterpenes from the Roots of Plectranthus hereroensis

Cited by 71 publications

References 10 publications

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Activity ofEugenia jambolana, an ethnomedical plant, against drug-resistant bacteria

Triagem in vitro de atividades antifúngica de óleos essenciais sobre leveduras de Candida como estratégia de prospecção e racionalização do uso de fitoterápicos

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