1976
DOI: 10.1016/0048-3575(76)90072-9
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Structure-activity study of herbicidal N-chloroacetyl-N-phenylglycine esters

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1979
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Cited by 20 publications
(10 citation statements)
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“…The steric bulk of the para-substituent seems to show undesirable effects on the potency of the activity at the ultimate site of herbicidal action. This situation is similar to the fact that the herbicidal activity of N-chloroacetyl-N-phenyl glycinates 19 ) and the auxin activity of phenoxyacetic acids 20 ) disappear when large substituent groups are introduced in the paraposition.…”
Section: Structure-activity Relationshipsupporting
confidence: 53%
“…The steric bulk of the para-substituent seems to show undesirable effects on the potency of the activity at the ultimate site of herbicidal action. This situation is similar to the fact that the herbicidal activity of N-chloroacetyl-N-phenyl glycinates 19 ) and the auxin activity of phenoxyacetic acids 20 ) disappear when large substituent groups are introduced in the paraposition.…”
Section: Structure-activity Relationshipsupporting
confidence: 53%
“…The different optimum n observed may also arise from a different membrane composition or structure. 19 ) The O"J term in Eq. (2) shows that the stronger the electron-donating power of the substituents, the greater was the antifungal activity.…”
Section: Resultsmentioning
confidence: 99%
“…Of the esters of aliphatic alcohols, the methyl (5) and ethyl (7) esters exhibited strong activity. The isopropyl (8) and n-propyl (9) esters still showed moderate activity, but nbutyl ester (10) showed only weak activity, indicating that the activity tended to decrease with an increase in number of carbon atoms in the alkyl group. The esters with alcohols having strong electron withdrawing substituents such as chloro, trifluoromethyl and cyano (11-13) also showed strong activity.…”
Section: Resultsmentioning
confidence: 99%