Structure Activity Relationship (SAR) of Some Benzoic Acid Derivatives from Plant Origin that Exhibit Anti-Sickling Properties in vitro - (Review)

Pierre, Luhata Lokadi; Moses, Namboole Munkombwe; Peter, Cheuka Mubanga

doi:10.4172/2329-6836.1000176

Cited by 1 publication

(1 citation statement)

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“…However, the phenolic content in FH was higher than that of FC, indicating that the inherent phenolic compounds are thermally stable. This observation is in line with the report of Semwal et al, 17 which showed that gingerol, a major constituent of ginger rhizome, is thermolabile while some antioxidant benzoic acid derivatives which have been previously reported in Fagara zanthoxyloides roots are relatively thermally stable 24,25 .…”

Section: Tpc (Gae Mg/g)supporting

confidence: 92%

Antioxidant Potential of Zingiber officinale Rhizome and Fagara zanthoxyloides Root Extracts and their Application in Soybean oil During Accelerated Storage

et al. 2019

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The oxidative instability of vegetable oils which contain polyunsaturated fatty acids and the health implication of synthetic antioxidants is the reason for the current intensive search for safer natural antioxidants. Hence, the total phenolic content and 2,2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging activity of Fagara zanthoxyloides root and Zingiber officinale rhizome have been comparatively evaluated. Zingiber officinale cold extract (GC) exhibited highest DPPH scavenging activity as well as the highest TPC while the hot extract from Fagara zanthoxyloides root (FH) had more phenolic content than its cold counterpart. Consequently, the anti-oxidative potential of refined soybean oil fortified with GC and FH was investigated at 65°C (accelerated storage temperature) for a lenght of 24 days. Established indicators such as peroxide, p-anisidine and total oxidation value (TOTOX) were used to monitor the extent of lipid deterioration with butylated hydroxyanisole (BHA) as the positive control. Generally, GC was more effective in stabilizing the soybean oil. After 24 days of storage, soybean oil fortified with GC, FH and BHA achieved 68.58%, 57.50% and 67.56% retardation in the formation of primary oxidation products respectively. The lowest TOTOX (146.38) value was also observed in GC supplemented oil, suggesting that GC could be effectively employed as a replacement for BHA in soybean oil preservation. Hence, extracts from Zingiber officinale rhizome and Fagara zanthoxyloides roots can be explored as sources of natural antioxidants for application in the food industry.

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Section: Tpc (Gae Mg/g)supporting

confidence: 92%