“…Hydantoins may be regarded as cyclodehydrated hydantoic acids (α-ureido acids), and this is reflected in their properties because both these compounds are readily interconvertible. Several natural or synthetic hydantoins themselves or their conjugates with other molecules exhibit diverse biological and pharmacological activities in medicinal, such as antimicrobial [11][12][13][14][15], antiviral [16][17][18], antitumor [19][20][21][22], antiarrhythmic [23][24][25][26], anticonvulsant [27][28][29][30][31][32][33][34], antihypertensive [35], antidiabetic [36][37][38][39], and agrochemical, such as herbicidal and fungicidal [40][41][42][43][44][45], applications. The studies on the biological activities of hydantoins has made great progress during the last three decades, and hydantoin derivatives have been therapeutically applied or are in the stage of investigation (Figure 1).…”