Structure-Activity Relationship Analysis of Novel Compounds Against Drug-Resistant Plasmodium Falciparum Strains

Abstract

The escalating issue of drug-resistant Plasmodium falciparum strains poses a significant challenge to malaria treatment. This research paper presents a comprehensive analysis of the Structure-Activity Relationship (SAR) of innovative compounds designed to combat drug-resistant malaria. Through systematic examination of the chemical structures and their biological activity, we aim to identify potential drug candidates that can effectively address this global health concern. Our study contributes to the ongoing efforts in antimalarial drug development, offering insights into the design of novel compounds that may prove instrumental in countering drug resistance among Plasmodium falciparum strains and improving the efficacy of malaria treatment strategies. Keywords: Plasmodium falciparum, Antimalarial Compounds, Drug Resistance, Chemical Structure Analysis, Novel Compounds