Abstract:Halogen atoms are typically located at the periphery of organic molecules and are thus ideally positioned to be involved in intermolecular interactions. Halogen bonding (XB) describes any interaction where halogen atoms function as electrophilic species. XB can be described by the general scheme D•••X-Y where X is the electrophilic halogen atom (Lewis acid, XB donor), D is a donor of electron density (Lewis base, XB acceptor), and Y is carbon, nitrogen, halogen, etc. (Scheme 1)[1]. The main features of the int… Show more
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