Structural studies of titanium(IV) picolinamide alkoxide and oxide derivatives

Abstract

Reactions have been carried out using the titanium(IV) precursors, TiCl4 and Ti(OiPr)4, with addition of two

Bis(N‐picolinamido)cobalt(II) Complexes Display Antifungal Activity toward Candida albicans and Aspergillus fumigatus

“…Synthesis of Co(II) complexes : The N ‐picolinamide ligands were synthesized via a known literature procedure from the condensation of picolinic acid with a functionalized aniline [41] . All ligands have been previously reported and 1 H NMR was used to confirm successful synthesis [42–50] . The bis( N ‐picolinamido)cobalt(II) diisothiocyanato complexes, [( L ) 2 Co(NCS) 2 ] 1 – 8 , were synthesized by the heating (15 mins) of cobalt(II) nitrate hexahydrate (1 eq.)…”

“… [41] All ligands have been previously reported and 1 H NMR was used to confirm successful synthesis. [ 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ] The bis( N ‐picolinamido)cobalt(II) diisothiocyanato complexes, [( L ) 2 Co(NCS) 2 ] 1 – 8 , were synthesized by the heating (15 mins) of cobalt(II) nitrate hexahydrate (1 eq.) with a functionalized N ‐picolinamide ligand ( L , 2 eq.…”

“…General : All ligands and complexes were synthesized under aerobic conditions. All ligands have previously been reported and 1 H NMR used to confirm successful synthesis [42–50] . All chemicals were supplied by Sigma‐Aldrich Chemical Co., Acros Organics and Alfa Aesar.…”

“…All ligands have previously been reported and 1 H NMR used to confirm successful synthesis. [ 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ] All chemicals were supplied by Sigma‐Aldrich Chemical Co., Acros Organics and Alfa Aesar. Deuterated NMR solvents were purchased from Sigma‐Aldrich Chemical Co. or Acros Organics.…”

Structural Chemistry of Titanium (IV) Oxo Clusters, Part 2: Clusters without Carboxylate or Phosphonate Ligands

“…The previously described Ti 3 O clusters with combinations of alkoxo and carboxylato ligands belong to this type. [1] The two shorter edges in the cluster Ti 3 O(OiPr) 8 [C 5 NH 4 -C(O) = NR] 2 (R = C 6 H 4 NO 2 ) [20] (Figure 2, right) are bridged by OR groups and the Ti atoms at the longer edge are chelated by the picolinamide ligands. Coordination of the titanium atoms in Ti 3 O(OiPr) 8 [3,3'-bis(methoxymethyl)binol] 2 (binol = dianion of 1,1'-bi-2-naphthol) is very similar, with the O À and OMe group of the methoxymethylnaphtholato units chelating the titanium atoms.…”