Structural properties of silver doped hydroxyapatite and their biocompatibility

Preparation and characterization of chitosan-silver/hydroxyapatite composite coatings onTiO2 nanotube for biomedical applications

“…4 shows the survey XPS scan spectra of the CSAgHAp coating and XPS narrow scan spectra of the Ag. The binding energies of Ca (2p, 347.3 eV), P (2p, 133.09 eV), and O (1s, 532.1 eV) are distinct in the XPS spectrum and two peaks of Ag were noted-Ag(3d 5/2 ) 367.5 eV and Ag(3d 3/2 ) 373.5 eV [8].…”

“…It has been incorporated into a variety organic materials [6,7]. Ciobanu et al found the Ag-HAp composite nanoparticles are effective in protecting macrophages from LPS induced cytotoxin in RAW 264.7 macrophage [8]. Our group recently reported that Ag-doped HAp composite coatings on anodized titanium exhibit increased antibacterial activities [9].…”

Cationic and Anionic Substitutions in Hydroxyapatite

“…By FT-IR and XRD analyses, it was demonstrated that Ag + ions substitute for Ca 2+ ions within the apatite lattice [141,161,181,186,187,189,199,[204][205][206]. Indeed, the effective Ag + incorporation within apatite lattice was testified by the identification of CaO, whose formation was ascribed to the oxidation of the free Ca 2+ ions, available in consequence of Ag + substitution for Ca 2+ within apatite lattice, during the thermal treatments [141].…”

“…In particular, it has been reported that Ag + ions substitution takes place for Ca 2+ preferentially in Ca(I) site of HAp, leading to an increase in the lattice parameters [161,187,189,192,206], due to the bigger Ag + ionic radius (0.128 nm vs 0.099 nm).…”

In vitro evaluation of the biological compatibility and antibacterial activity of a bone substitute material consisting of silver‐doped hydroxyapatite and Bio‐Oss®

“…17,18 In accordance with x 5 0.5 in the chemical DAP) (Aladdin Reagent, China) was dissolved in deionized water; ammonia (Aladdin Reagent, China) was used to regulate the pH of the DAP solution at 10. Then, the DAP solution was titrated into solution 1 at room temperature, after which the sediment was washed repeatedly with deionized water until the pH decreased to 7.…”