The purpose of this paper is to construct a methodology which can produce a lightweight panel structure while being satisfied with more than one constraint by using some simple model. In this study, we chose a problem including bending stiffness and the 1 st order eigen frequency as constraints and volume minimization as objective function among basic performances which a vehicle requires. So far, we have been trying to solve the problem by using a method consisting of Fully Stressed Design (FSD) and Genetic Algorithm (GA). FSD is an optimization which evaluates only stiffness of a structure based on relationship between thickness and stress, while GA, a broad array method, can have various number of objective functions and constraints. Prior to this study, the authors found a process was effective that stresses on the elements were to be equalized in the 1st step by applying FSD that made an individual superior on static stiffness. In this study, proposed method, which includes a process of equalization on normalized stresses on eigen vibrations, are added to that of static stresses in the 1st step. In the 2nd step, GA is selected. GA conducts operations, such as select, crossing, and mutation repeatedly until this attains a final solution. As for the model, we chose a sandwich panel which is equipped with top and bottom plates and interlayer lattice stiffeners. The reason for this selection is that the sandwich panel is lightweight and superior to stiffness, dumping, and strength. As a result, the obtained model presents a lightweight structure while being satisfied with the requirements of both stiffness and eigen frequency. Moreover, the proposed method attains optimized results earlier than GA without using FSD.