Abstract:Tumor Differentiation Factor (TDF) is a pituitary protein, which is secreted into the blood stream and targets breast and prostate. The end effect of TDF on these tissues is differentiation of breast and prostate cells. However, it is not yet clear how TDF induces cell differentiation. Studies in our laboratory determined that the potential TDF receptor candidates are: HSPA8, a member of the 70 kDa heat shock protein family and HSP90 protein. Our previous studies also indicated that TDF may have an inducible r… Show more
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