Structural, functional, and antioxidant properties of water-soluble polysaccharides from potatoes peels

Jeddou, Khawla Ben; Châari, Fatma; Maktouf, Sameh; Nouri-Ellouz, Oumèma; Helbert, Claire Boisset; Ghorbel, Raoudha

doi:10.1016/j.foodchem.2016.02.108

Cited by 260 publications

(113 citation statements)

References 34 publications

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“…The WHC of TPS–FJ and TPS–SC were 7.56 and 9.15 g water g −1 dry polysaccharide, respectively (Table ). The WHC was much higher than those of the isolated acorn polysaccharide (4.33 g water g −1 DM) (Tadayoni et al ., ) and water‐soluble polysaccharides from potatoes peels (4.10 g water g −1 ) (Jeddou et al ., ). Water holding capacity refers to its porous matrix structure and its ability to hold water in its matrix.…”

Section: Resultsmentioning

confidence: 97%

Comparison of structural, antioxidant and immuno‐stimulating activities of polysaccharides from Tremella fuciformis in two different regions of China

Pan

Sun

Wang

et al. 2018

Int J of Food Sci Tech

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Summary In this study, we compared the chemical structure, antioxidant and immuno‐stimulating activities of two polysaccharides, TPS–FJ and TPS–SC, extracted from Tremella fuciformis from two of the major cultivation regions of China. TPS–FJ and TPS–SC contained protein and high uronic acid. Average molecular weights of TPS–FJ and TPS–SC were 45 461 and 25 981 kDa, respectively. A triple‐helix conformation was exhibited by TPS–FJ but not by TPS–SC. TPS–FJ and TPS–SC contained same monosaccharides but in different ratios. Both the polysaccharides displayed characteristic polysaccharide bands in their Fourier transform infrared and NMR spectra, shown high water and oil holding capacity, and retained antioxidant potential after simulated gastrointestinal digestion in vitro. TPS–FJ significantly (P < 0.05) stimulated the nitric oxide, tumour necrosis factor‐α and interleukin‐6 production of RAW 264.7 cells with higher reactions than those of TPS–SC in vitro. Thus, Tremella fuciformis polysaccharide can be used as a potential antioxidant and immunomodulatory ingredient in food industry.

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Section: Resultsmentioning

confidence: 97%

Comparison of structural, antioxidant and immuno‐stimulating activities of polysaccharides from Tremella fuciformis in two different regions of China

Pan

Sun

Wang

et al. 2018

Int J of Food Sci Tech

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“…However, the drugs performed in clinic, especially single-component chemicals, display severe adverse effects including general malaise and/or neurotoxicity (11,12), which is hard to meet the requirements of immunosuppressive patients. Dietary polysaccharides from natural products are getting more attention due to their health benefits and low toxicity (13,14), which have been confirmed to exhibit multiple immunomodulatory effects (15,16). Gloeostereum incarnatum, a precious edible mushroom, parasitizes broad-leaved wood in northern Japan and northern China (17).…”

Section: Introductionmentioning

confidence: 99%

The investigation of immunomodulatory activities of Gloeostereumï¿½incaratum polysaccharides in cyclophosphamide-induced immunosuppression mice

Wang

et al. 2018

Exp Ther Med

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Abstract. Gloeostereum incarnatum, a precious edible mushroom, displays anti-bacterial and anti-inflammatory activities; however, its immunomodulatory effect has not been studied yet. The present study aimed to investigate whether polysaccharide compositions of G. incarnatum polysaccharides (GIPS) possess immunomodulatory and immuno-enhancing effects in a Cyclophosphamide monohydrate (CTX)-induced BALB/c mice model. The 28-day GIPS administration at doses of 0.1, 0.3 and 0.9 g/kg remarkably reversed the bodyweight loss, increased the thymic index and promoted T lymphocyte proliferation in CTX-induced immunosuppressed mice. GIPS significantly raised the serum levels of immunoglobulin (Ig) A and IgG, promoted the production of interleukins (ILs), including IL-2, IL-3 and IL-6, interferons, including interferon (IFN)-α and IFN-γ, and monocyte chemotactic protein 1 in the spleen, which resulted in accelerating recovery of immunosuppression. Finally, GIPS showed anti-oxidative effects indicated by the increased superoxide dismutase levels in the serum and spleen, and the reduced level of reactive oxygen species in the spleen. The results of the current study demonstrated that GIPS positively adjusts the immune system, which may serve as a potential immunostimulatory agent. IntroductionThe immune system, a complex self-regulation system, is responsible for the defense function of organism to prevent outside pathogens, remove the waste material and maintain the monitoring function for malignant cells (1). The immune system is highly sensitive (2), and shows impaired immune responsiveness to pathogen invasion, during which, immune cells are activated and secret pro-inflammatory mediators including interleukins (ILs) and interferons (INFs) are increased (3,4). And immunity closely related to oxidative stress, which could lead to aberrant expression of inflammatory cytokines and chemokines (5). Cyclophosphamide monohydrate (CTX), a cancer chemotherapeutic agent, facilitates cell apoptosis and decreases the homeostatic proliferation of regulatory T cells (6), which has been widely used in the establishment of immunosuppressive animal models (7-9).Previous researchers focus their studies on searching immunomodulatory agents for years (10). However, the drugs performed in clinic, especially single-component chemicals, display severe adverse effects including general malaise and/or neurotoxicity (11,12), which is hard to meet the requirements of immunosuppressive patients. Dietary polysaccharides from natural products are getting more attention due to their health benefits and low toxicity (13,14), which have been confirmed to exhibit multiple immunomodulatory effects (15,16). Gloeostereum incarnatum, a precious edible mushroom, parasitizes broad-leaved wood in northern Japan and northern China (17). Traditionally, G. incarnatum preparation is widely used for the treatment for enteritis, dysentery and gastric ulcer (18). Polysaccharides obtained from G. incarnatum fruiting body have been reported to possess anti-tumor and ant...

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“…It has been established that the lymphatic absorption of free fatty acids could be effectively interfered by binding with functional components . Some polysaccharides were demonstrated to be capable of binding with saturated fat, such as chitosans, water‐soluble polysaccharides from potato peels and chickpea flour . However, few researchers have attempted to investigate the interactions of fat with GA and TA.…”

Section: Resultsmentioning

confidence: 99%

In vitro studies on the interactions of blood lipid level‐related biological molecules with gallic acid and tannic acid

Zeng

Sheng

et al. 2019

J Sci Food Agric

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BACKGROUND To provide the scientific evidence for a possible new mechanism of hypolipidemic effects of gallic acid (GA) and tannic acid (TA), the binding capacity of GA and TA with blood lipid level‐related biological molecules, including fat, cholesterol and cholates, were investigated in vitro. Additionally, we attempted to study the interactions of cholates with GA and TA by spectroscopic methods, high‐performance liquid chromatography electrospray‐ionization mass spectrometry (HPLC‐ESI‐MS) analysis and molecular modeling studies. RESULTS Our results demonstrated that both GA and TA were capable of binding with the blood lipid level‐related biological molecules in vitro. The fat‐binding capacity of TA was 122.1% that of GA when the addition of polyphenol was 90 mg. The inhibitory effects of GA and TA on the cholesterol solubility in mixed micelles and liquid egg yolk exhibited a dose‐dependent relationship (0.5–2.0 mg mL−1). In cholate‐binding tests, TA showed higher affinity for sodium cholate than GA at a concentration of 2.0 mg mL−1, while no significant difference in the affinity for sodium deoxycholate was found between GA and TA. Moreover, the data of spectroscopic methods, HPLC‐ESI‐MS analysis and molecular modeling studies indicated that GA and TA might precipitate cholates through hydrophobic interactions and intermolecular hydrogen bonds rather than covalent bonds. CONCLUSION The findings of the present study suggested that the binding capacity of GA and TA with blood lipid level‐related biological molecules might play a crucial role in their hypolipidemic effects in animals. © 2019 Society of Chemical Industry

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Structural, functional, and antioxidant properties of water-soluble polysaccharides from potatoes peels

Cited by 260 publications

References 34 publications

Comparison of structural, antioxidant and immuno‐stimulating activities of polysaccharides from Tremella fuciformis in two different regions of China

Comparison of structural, antioxidant and immuno‐stimulating activities of polysaccharides from Tremella fuciformis in two different regions of China

The investigation of immunomodulatory activities of Gloeostereumï¿½incaratum polysaccharides in cyclophosphamide-induced immunosuppression mice

In vitro studies on the interactions of blood lipid level‐related biological molecules with gallic acid and tannic acid

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