The effects of two conventional heat treatments and one innovative processing by laser surface remelting of modified X37CrMoV5-1 tool steel on its abrasion wear resistance were investigated. Conventional heat treatments consisted of quenching from 990 °C, individually followed by two different tempering treatments to achieve secondary hardness either at 520 °C or 560 °C. Laser surface remelting was performed using optimized parameters of continuous laser beam scanning mode. The results showed that the highest wear resistance was obtained for almost carbide-free, surface remelted microstructure with the highest hardness due to microstructural refinement and martensitic transformation hardening. The observed differences in wear resistance among individual material states are discussed in relation to their microstructures, hardness, and wear mechanisms characteristics.