Structural diversity in copper(II) complexes of bis(thiosemicarbazone) and bis(semicarbazone) ligands

Seleem, H.S.; El‐Shetary, B. A.; Khalil, Saied M. E.; Mostafa, M. M.; Shebl, Magdy

doi:10.1080/00958970512331334269

Cited by 90 publications

(43 citation statements)

References 20 publications

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“…In complexes 3, 10, and 11 the new bands observed in the ranges 1,360-1,384 and 1,058-1,203 cm -1 may be assigned to the monodentate NO 3 -group [41,42]. On the other hand, complex 2 showed a new band at 1,423 cm -1 that may be assigned to ionic NO 3 -group [43,44]. The mixed 8-hydroxyquinoline complexes 5 and 13 showed new bands at 1,499 and 1,497 cm -1 , respectively, which may be assigned to the coordinated C=N group of the 8-hydroxyquinoline moiety [43,45,46].…”

Section: Ir Spectramentioning

confidence: 77%

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Shebl

Khalil

2014

Monatsh Chem

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Two pentadentate carbohydrazone ligands, H 2 L 1 and H 2 L 2 , were prepared by the reaction of the bifunctional compound carbohydrazide with 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde, respectively. Reactions of the ligands with oxovanadium(IV), cerium(III), thorium(IV), and dioxouranium(VI) ions yielded binary complexes. Reactions of the ligands with the dioxouranium(VI) ion in the presence of secondary ligands (8-hydroxyquinoline, glycine, salicylaldehyde, or benzoylacetone) yielded ternary complexes. The ligands and metal complexes were characterized by different techniques such as elemental and thermal analyses, IR, 1 H and 13 C NMR, electronic, ESR, mass spectra, and powder XRD as well as magnetic susceptibility and conductivity measurements. The coordinating sites are phenolic oxygen, azomethine nitrogen, and carbonyl oxygen. In complexes, the ligands act as dibasic pentadentate except ternary dioxouranium(VI) complexes, obtained using glycine or benzoylacetone, in which the ligands act as monobasic pentadentate. The XRD patterns for the H 2 L 1 ligand, its binary dioxouranium(VI) complex, and its 8-hydroxyquinoline ternary complex indicate crystalline nature and the grain size was estimated. The H 2 L 1 ligand and its binary complex have triclinic systems while the ternary complex has a monoclinic system with different unit-cell parameters. The ligands and some of their metal complexes showed antimicrobial activity toward some Gram-positive and Gram-negative bacteria, yeast (Candida albicans), and fungus (Aspergillus fumigatus), and MIC values were determined. The DNA binding properties of the oxovanadium(IV) complexes of H 2 L 1 and H 2 L 2 ligands were investigated by electronic absorption spectroscopy and viscosity measurements. The results indicated that these complexes bind to DNA via an intercalation binding mode with an intrinsic binding constant K b of 2.55 9 10 4 and 3 9 10 4 M -1 , respectively.

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Section: Ir Spectramentioning

confidence: 77%

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Shebl

Khalil

2014

Monatsh Chem

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“…Ni II Complexes (6)(7)(8) The reaction of Ni(NO 3 ) 2 ·6H 2 O with the poly-H 3 L ligand in the absence and presence of Phen or Bpy afforded paramagnetic binuclear complexes/each monomeric units (6)(7)(8). Their visible spectra in DMF showed strong peaks in the region of 424-430 nm assignable to ν 3 transition, 3 A 2g → 3 T 1g (P), and shoulders in the region of 540-556 nm (Table 3) .…”

Section: Cobalt Complexes (9-12)mentioning

confidence: 99%

“…Herein, we report a novel rigid pentadentate O 2 N 2 S polymeric ligand (H 3 L) bearing both hard and soft donor atoms and its metal complexes with Cu II , Co II , and Ni II ions. This study is a continuation of our interest on thiosemicarbazones and semicarbazones [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of a novel series of metallothiocarbohydrazone polymers and their adducts

Seleem

El‐Shetary

Shebl

2007

Heteroatom Chemistry

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“…Broad EPR spectra of this kind were reported earlier for the complexes having large organic ligand substituents with different donor atoms having considerable covalent character for metal-ligand bonds (Kulkarni et al, 2010;Seleem et al, 2005).…”

Section: Epr Spectral Analysismentioning

confidence: 99%

Transition metal complexes of thiosemicarbazones with quinoxaline hub: an emphasis on antidiabetic property

Kulkarni

Revankar

Kirasur³

et al. 2011

Med Chem Res

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New transition metal complexes of quinoxaline-thiosemicarbazone ligands were prepared and characterised by spectroanalytical techniques. The ligands L 1 H 2 and L 2 H 2 were obtained by the reaction of quinoxaline-2.3(1,4H)-dione with methyl and phenyl thiosemicarbazide, respectively. All the complexes are found to be monomeric in nature and have tetrahedral geometry. The copper complexes have shown redox responses in the applied voltage range, whereas the ligands and other complexes are electrochemically innocent. The ligands, copper and zinc complexes are explored for antidiabetic activity in the diabetes-induced Wister rats. Evaluation of antidiabetic activity was done by blood-glucose test and oral glucose tolerance test; few compounds have exhibited significant antidiabetic activity and posses low toxicity with a high safety profile.

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Structural diversity in copper(II) complexes of bis(thiosemicarbazone) and bis(semicarbazone) ligands

Cited by 90 publications

References 20 publications

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Synthesis, spectral, X-ray diffraction, antimicrobial studies, and DNA binding properties of binary and ternary complexes of pentadentate N2O3 carbohydrazone ligands

Synthesis and characterization of a novel series of metallothiocarbohydrazone polymers and their adducts

Transition metal complexes of thiosemicarbazones with quinoxaline hub: an emphasis on antidiabetic property

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