Sensing technology and sensor development have received increased attention in the recent years, and a number of types of sensors have been developed for various applications for materials and structures. In this paper, we will discuss the concept of combining sensing of global vibration and local infrared imaging techniques. The global vibration-based techniques determine the health condition of structures by the changes in their dynamic properties or responses to external disturbs or excitations. Infrared Imaging is introduced here to detect local defects or problems so that to provide more direct and accurate assessment about the severity and extent of the damage. The progress on developing a hybrid structural health monitoring system is presented through the results on both the global sensing algorithm study and local infrared imaging investigation on a steel C channel.