Structural characterization, α-glucosidase inhibitory and DPPH scavenging activities of polysaccharides from guava

Zhang, Zi-Ling; Kong, Fanrong; Ni, Hui; Mo, Zhixian; Wan, Jian‐Bo; Hua, Dehong; Yan, Chunyan

doi:10.1016/j.carbpol.2016.02.030

Cited by 130 publications

(53 citation statements)

References 47 publications

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“…Reaction kinetics of scavenging capacity against DPPH free radical of EEO DPPH radicals exhibit a purple color in ethanol solution, and their color decreases when they react with antioxidants. Different antioxidants have different rates of scavenging DPPH·free radical (Claudia et al, 2016;Zhang et al, 2016). The results of the reductive capabilities of EEO at different concentrations are presented in Figure 7.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Inclusion Complex of Exocarpium Citri Grandis Essential Oil with β‐Cyclodextrin: Characterization, Stability, and Antioxidant Activity

Qin

Zhang

et al. 2019

Journal of Food Science

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The purpose of this study was to produce and characterize an inclusion complex between β‐cyclodextrin (β‐CD) and Exocarpium Citri Grandis essential oil (EEO), and to evaluate its antioxidant properties. The volatile compounds of EEO were characterized by gas chromatography‐mass spectrometer. A comparison of the β‐CD, EEO, and the physical mixture with the inclusion complex revealed differences in their thermal stabilities and morphologies, which confirmed the formation of the β‐CD‐EEO inclusion complex. Complexed with β‐CD, the β‐CD‐EEO inclusion complex showed a higher stability and antioxidant activity when compared with physical mixture and EEO. Therefore, β‐CD can be used to form inclusion complexes with EEO to expand its potential applications in the food and drug industries. Practical Application Exocarpium Citri Grandis is rich in essential oil and other ingredients. The optimized extraction, constituent composition, and encapsulation of EEO in β‐CD were investigated in this study. The results showed that the encapsulation process increased the antioxidant activity and stability of EEO, which provides both fundamental and practical knowledge for the application of EEO in the food and drug industries.

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Section: Antioxidant Activitymentioning

confidence: 99%

Inclusion Complex of Exocarpium Citri Grandis Essential Oil with β‐Cyclodextrin: Characterization, Stability, and Antioxidant Activity

Qin

Zhang

et al. 2019

Journal of Food Science

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“…Moreover, Deguchi and Miyazaki [58] suggested that the component that inhibited the in vitro activities of α-glucosidase enzymes in guava extract was a polymerized polyphenol. In addition, polysaccharides from guava leaves also exhibited α-glucosidase inhibition [59]. …”

Section: Pharmacological Propertiesmentioning

confidence: 99%

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Díaz‐de‐Cerio

Verardo

Gómez-Caravaca

et al. 2017

IJMS

137

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Today, there is increasing interest in discovering new bioactive compounds derived from ethnomedicine. Preparations of guava (Psidium guajava L.) leaves have traditionally been used to manage several diseases. The pharmacological research in vitro as well as in vivo has been widely used to demonstrate the potential of the extracts from the leaves for the co-treatment of different ailments with high prevalence worldwide, upholding the traditional medicine in cases such as diabetes mellitus, cardiovascular diseases, cancer, and parasitic infections. Moreover, the biological activity has been attributed to the bioactive composition of the leaves, to some specific phytochemical subclasses, or even to individual compounds. Phenolic compounds in guava leaves have been credited with regulating blood-glucose levels. Thus, the aim of the present review was to compile results from in vitro and in vivo studies carried out with guava leaves over the last decade, relating the effects to their clinical applications in order to focus further research for finding individual bioactive compounds. Some food applications (guava tea and supplementary feed for aquaculture) and some clinical, in vitro, and in vivo outcomes are also included.

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“…In 2016, a novel polysaccharide GP90‐1B (Figure ), with a nona‐decasaccharide repeating unit, was isolated from the fruit of Psidium guajava , which is a well‐known medicinal plant for the treatment of various ailments such as diabetes, diarrhea, ulcers, and rheumatism . The unique structural features of the glycans of GP90‐1B include the following: 1) a challenging 2,3,5‐branched l ‐arabinofuranose (Ara f ) motif at the reducing end; 2) two 1,2‐ cis ‐glucosidic linkages, which are challenging to construct in a highly stereoselective manner; 3) a long arabinofuranose chain with a 13 α‐(1→5)‐linked Ara f motif at the nonreducing end.…”

Section: Introductionmentioning

confidence: 99%

Modular Synthesis of Nona‐Decasaccharide Motif from Psidium guajava Polysaccharides: Orthogonal One‐Pot Glycosylation Strategy

et al. 2020

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The synthesis of long, branched, and complex carbohydrate sequences remains a challenging task in chemical synthesis. Reported here is an efficient and modular one‐pot synthesis of a nona‐decasaccharide and shorter sequences from Psidium guajava polysaccharides, which have the potent α‐glucosidase inhibitory activity. The synthetic strategy features: 1) several one‐pot glycosylation reactions on the basis of N‐phenyltrifluoroacetimidate (PTFAI) and Yu glycosylation to streamline the chemical synthesis of oligosaccharides, 2) the successful and efficient assembly sequences (first O3′, second O5′, final O2′) toward the challenging 2,3,5‐branched Araf motif, 3) the stereoselective 1,2‐cis‐glucosylation by reagent control, and 4) the convergent [6+6+7] one‐pot coupling reaction for the final assembly of the target nona‐decasaccharide. This orthogonal one‐pot glycosylation strategy can streamline the chemical synthesis of long, branched, and complicated carbohydrate chains.

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Structural characterization, α-glucosidase inhibitory and DPPH scavenging activities of polysaccharides from guava

Cited by 130 publications

References 47 publications

Inclusion Complex of Exocarpium Citri Grandis Essential Oil with β‐Cyclodextrin: Characterization, Stability, and Antioxidant Activity

Inclusion Complex of Exocarpium Citri Grandis Essential Oil with β‐Cyclodextrin: Characterization, Stability, and Antioxidant Activity

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Modular Synthesis of Nona‐Decasaccharide Motif from Psidium guajava Polysaccharides: Orthogonal One‐Pot Glycosylation Strategy

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