2019
DOI: 10.1039/c9ra03965a
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Structural characterization of ginseng cyclopeptides and detection of capability to induce apoptosis in gastrointestinal cancer cells

Abstract: Gastrointestinal tumors are the most frequently diagnosed malignancy and the second highest contributor to cancer mortality.

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Cited by 4 publications
(4 citation statements)
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“…Healthcare. Assuming that the random variable X obeys the logistic distribution, the cumulative distribution function of X is as follows [4,5]:…”
Section: Exercise Intervention and Gastrointestinal Tumorsmentioning
confidence: 99%
“…Healthcare. Assuming that the random variable X obeys the logistic distribution, the cumulative distribution function of X is as follows [4,5]:…”
Section: Exercise Intervention and Gastrointestinal Tumorsmentioning
confidence: 99%
“…Seven novel ginseng cyclopeptides (GCPs) were isolated and showed anti-proliferative activities in gastric cancer SGC-7901 cells, in which GCP-1 (86) showed the most potency with IC 50 value of 37.8 µM. Regarding its molecular mechanism, it induces apoptosis by activating the caspases and regulating thioredoxin (Trx)-dependent pathways, including signal-regulating kinase 1 (ASK1), mitogen-activated protein kinases (MAPKs)-p38 and JNK pathways [138].…”
Section: Terrestrial Plant-derived Anticancer Cyclopeptidesmentioning
confidence: 99%
“…[ [181][182][183][184][185] Ohmyungsamycins A (121) and B (122) Streptomyces sp. [196] Sungsanpin (138) Streptomyces sp. Anti-invasion effects on A549 cell.…”
Section: Anticancer Cyclopeptides Derived From Cyanobacteriamentioning
confidence: 99%
“…The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to a significant amount of unattributed text overlap with articles by different author groups, including articles published in Acta Pharmacologica Sinica by Yu-ping Zhu et al 1 and RSC Advances by Zhuo Liu et al 2 …”
mentioning
confidence: 99%