2005
DOI: 10.1016/j.jasms.2004.12.009
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Structural characterization and regiochemical differentiation of α-cyanoethylindole isomers in the gas phase

Abstract: Mass spectrometry and tandem mass spectrometry techniques have been used to study the gas phase ion chemistry of isomeric ␣-cyanoethylindoles obtained by photochemical reactions. Both the fragmentation reactions occurring in the ion source, as well as metastable decompositions produced by the molecular and selected fragment ions, have allowed us to structurally characterize and differentiate each isomer from the others. The experiments, carried out also on deuterium labeled analogs, have shown the role exerted… Show more

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Cited by 7 publications
(3 citation statements)
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“…Nonetheless, some positional isomers could still be distinguished based on the relative abundances of these product ions. Isomeric differentiation of heterocyclic systems has also been reported based on major11 or on minor12–15 ions in MS/MS spectra, arising from regiospecific reactions. Alternatively, the use of ion‐molecule reactions in the gas phase was shown to allow the direct mass spectrometric positional assignment of configurations within homologous series 16, 17…”
mentioning
confidence: 99%
“…Nonetheless, some positional isomers could still be distinguished based on the relative abundances of these product ions. Isomeric differentiation of heterocyclic systems has also been reported based on major11 or on minor12–15 ions in MS/MS spectra, arising from regiospecific reactions. Alternatively, the use of ion‐molecule reactions in the gas phase was shown to allow the direct mass spectrometric positional assignment of configurations within homologous series 16, 17…”
mentioning
confidence: 99%
“…By continuing our research on gas-phase ion chemistry of organic molecules, 9 we wish to report here on the positive electrospray ionization (ESI) MS n n D 1-3 spectra, obtained inside an ion trap, of fluoroalkyl triazines 1-3 (Scheme 1) whose synthesis has been published recently. 10 ESI measurements have been carried out on a LCQ-DECA (ThermoFinnigan, San Jose, CA).…”
mentioning
confidence: 99%
“…In the frame of a research aimed at studying the gas-phase ion chemistry of heterocyclic molecules, [22,23] we wish to report here the gas-phase behavior of compounds 1-4 (Scheme 1) and of their deoxygenated derivatives. The study has been carried out by using an electron ionization (EI) source internal to a quadrupole ion trap.…”
Section: Introductionmentioning
confidence: 99%