Structural characterization and properties of polyols plasticized chitosan films

Ma, Xianguang; Qiao, Chuanling; Wang, Xujie; Yao, Jinshui; Xu, Jing

doi:10.1016/j.ijbiomac.2019.05.158

Cited by 87 publications

(52 citation statements)

References 34 publications

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“…While the endothermic peaks of chitosan scaffold transitioned towards lower temperatures, the exothermic decomposition peak moved to higher temperatures (Table 1)-confirming the enhanced stability of the blends against the individual components. A decrease in both the endothermic peaks in the blends (corresponding to chitosan and mPEG derivatives) may be due to the plasticizing effect of mPEG on the chitosan indicating improved flexibility [49][50][51] (Table 1). Another important thermal event within the blend scaffolds involved the notable transition of large exothermic peaks of mPEG, mPEG-CHO and mPEG-COOH at 252.15, 249.59 and 290.97 °C to 165.80, 167.50 and 176.88 °C, respectively.…”

Section: Resultsmentioning

confidence: 99%

Macroporous chitosan/methoxypoly(ethylene glycol) based cryosponges with unique morphology for tissue engineering applications

Kumar

Pillay

Choonara

2021

Sci Rep

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Three-dimensional porous scaffolds are widely employed in tissue engineering and regenerative medicine for their ability to carry bioactives and cells; and for their platform properties to allow for bridging-the-gap within an injured tissue. This study describes the effect of various methoxypolyethylene glycol (mPEG) derivatives (mPEG (-OCH3 functionality), mPEG-aldehyde (mPEG-CHO) and mPEG-acetic acid (mPEG-COOH)) on the morphology and physical properties of chemically crosslinked, semi-interpenetrating polymer network (IPN), chitosan (CHT)/mPEG blend cryosponges. Physicochemical and molecular characterization revealed that the –CHO and –COOH functional groups in mPEG derivatives interacted with the –NH2 functionality of the chitosan chain. The distinguishing feature of the cryosponges was their unique morphological features such as fringe thread-, pebble-, curved quartz crystal-, crystal flower-; and canyon-like structures. The morphological data was well corroborated by the image processing data and physisorption curves corresponding to Type II isotherm with open hysteresis loops. Functionalization of mPEG had no evident influence on the macro-mechanical properties of the cryosponges but increased the matrix strength as determined by the rheomechanical analyses. The cryosponges were able to deliver bioactives (dexamethasone and curcumin) over 10 days, showed varied matrix degradation profiles, and supported neuronal cells on the matrix surface. In addition, in silico simulations confirmed the compatibility and molecular stability of the CHT/mPEG blend compositions. In conclusion, the study confirmed that significant morphological variations may be induced by minimal functionalization and crosslinking of biomaterials.

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Section: Resultsmentioning

confidence: 99%

Macroporous chitosan/methoxypoly(ethylene glycol) based cryosponges with unique morphology for tissue engineering applications

Kumar

Pillay

Choonara

2021

Sci Rep

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“…8 In this regard, natural derived polyols can be used as starting materials in polymer products (PU adhesives, PU films, epoxy resins, and PU foams). [9][10][11][12][13] In this context, rigid PU foams (RPUFs) are one of the most commercial polymeric foams since they are used in a wide range of applications (automotive, insulation, and construction industry) due to their excellent thermal and mechanical properties. 14 In fact, RPUFs accounts for about 23% of all PU production.…”

Section: Introductionmentioning

confidence: 99%

“…Nevertheless, in the context of circular economy, the growing demand for the use of raw materials through sustainable and environmentally friendly processes offers an excellent opportunity for natural derived polyols to enter the polyurethane (PU) market 8 . In this regard, natural derived polyols can be used as starting materials in polymer products (PU adhesives, PU films, epoxy resins, and PU foams) 9–13 …”

Section: Introductionmentioning

confidence: 99%

Insulating rigid polyurethane foams from laurel tree pruning based polyol

Rincón

Balu

Luque

et al. 2020

J of Applied Polymer Sci

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The present work deals with the production of a natural polyol from laurel tree pruning waste, aiming the preparation of polyurethane foams. The obtained bio-polyol was characterized and applied into foams studying the influence of the isocyanate used and the addition of the physical blowing agent. The incorporation of the polyol allowed 40% polyol substitution for those foams in which TDI was used, and up to 60% using MDI. Apparent density, cell morphology, mechanical, and thermal properties were evaluated. Mechanical and thermal properties of the foams improve to a greater amount of polyol in the matrix. Specifically, the best thermal and mechanical properties (274.99 and 7275.91 kPa for compressive strength and Young Modulus, respectively) were obtained with 50% polyol substitution (0.63 R NCO/OH). Foams showed small, well-defined cell morphology. Laurel derived polyol can be used for the preparation of foams using MDI, since the mechanical, and thermal properties are promising for obtaining insulation materials in the construction industry.

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“…Chitosan, (1-4)-2-amino-2-deoxy-b-d-glucan, is one of the marine bioactive compounds, which can be readily prepared by the N-deacetylation from chitin [2,9,10]. In the last few years, chitosan has attracted significant attention in chemical industry, maquillage, papermaking, and food science because of its excellent physical and chemical properties such as biodegradability, non-toxicity, biocompatibility, bioactivity and other properties [11,12]. However, the weak bioactivity and poor water solubility could greatly limit the further industrial application of chitosan.…”

Section: Introductionmentioning

confidence: 99%

Modification of Hydroxypropyltrimethyl Ammonium Chitosan with Organic Acid: Synthesis, Characterization, and Antioxidant Activity

Tan

Zhang

et al. 2020

Polymers

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A novel and green method for the preparation of chitosan derivatives bearing organic acids was reported in this paper. In order to improve the antioxidant activity of chitosan, eight different hydroxypropyltrimethyl ammonium chitosan derivatives were successfully designed and synthesized via introducing of organic acids onto chitosan by mild and non-toxic ion exchange. The data of Fourier Transform Infrared (FTIR), 13C Nuclear Magnetic Resonance (NMR), 1H NMR, and elemental analysis for chitosan derivatives indicated the successful conjugation of organic acid salt with hydroxypropyltrimethyl ammonium chloride chitosan (HACC). Meanwhile, the antioxidant activity of the chitosan derivatives was evaluated in vitro. The results indicated that the chitosan derivatives possessed dramatic enhancements in DPPH-radical scavenging activity, superoxide-radical scavenging activity, hydroxyl radical scavenging ability, and reducing power. Furthermore, the cytotoxicity of the synthesized compounds was investigated in vitro on L929 cells and showed low cytotoxicity. Thus, the enhanced antioxidant property of all novel chitosan products might be a great advantage, while applied in a wide range of applications in the form of antioxidant in biomedical, food, and cosmetic industry.

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Structural characterization and properties of polyols plasticized chitosan films

Cited by 87 publications

References 34 publications

Macroporous chitosan/methoxypoly(ethylene glycol) based cryosponges with unique morphology for tissue engineering applications

Macroporous chitosan/methoxypoly(ethylene glycol) based cryosponges with unique morphology for tissue engineering applications

Insulating rigid polyurethane foams from laurel tree pruning based polyol

Modification of Hydroxypropyltrimethyl Ammonium Chitosan with Organic Acid: Synthesis, Characterization, and Antioxidant Activity

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