Structural characterization and evaluation of the antioxidant activities of polysaccharides extracted from Qingzhuan brick tea

Yang, Xiaoyong; Huang, Mingjun; Qin, Caiqin; Lv, Bin; Qing-li, Mao; Z, Liu

doi:10.1016/j.ijbiomac.2017.03.189

Cited by 110 publications

(64 citation statements)

References 29 publications

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“…The absorption peak at 1000–1200 cm −1 indicated that each sample contained a pyran structure, which revealed a peak of Gal at 1072 cm −1 . The peak near 889 cm −1 indicated that pyran possesses a β‐type glycosidic bond, whereas the peak at 500–800 cm −1 was also a result of the vibration of the pyranose skeleton . The peak near 750–780 cm −1 contained the characteristic absorption of Ara .…”

Section: Resultsmentioning

confidence: 99%

“…42,43 The peak near 889 cm −1 indicated that pyran possesses a -type glycosidic bond, 44 whereas the peak at 500-800 cm −1 was also a result of the vibration of the pyranose skeleton. 45 The peak near 750-780 cm −1 contained the characteristic absorption of Ara. 46 The FT-IR spectra illustrated that each sample contained the same functional group.…”

Section: Ft-ir Analysismentioning

confidence: 99%

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Antitumor bioactivity of porphyran extracted from Pyropia yezoensis Chonsoo2 on human cancer cell lines

Yan

et al. 2019

J Sci Food Agric

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BACKGROUND Pyropia yezoensis, rich in porphyran, is a medicine‐edible red alga. In the present study, the physicochemical characteristics, conformational states and antitumor activities of a novel porphyran extracted from the high‐yield algal strain Pyropia yezoensis Chonsoo2 and its two degraded derivatives by gamma irradiation were investigated. RESULTS Pyropia yezoensis porphyran is a water‐soluble, triple‐helical sulfated hetero‐galactopyranose, named PYP. PYP was degraded by gamma irradiation at 20 kGy and 50 kGy, giving two low molecular weight derivatives comprising PYP‐20 and PYP‐50, respectively. PYP with a higher molecular weight has a solution conformation different from PYP‐20 and PYP‐50. Three porphyrans had no toxicity in normal human liver cells (HL‐7702) and showed antitumor effects on Hep3B, HeLa and MDA‐MB‐231. They had better antitumor against HeLa cells, exhibiting a similar inhibition ratio compared to 5‐fluorouracil, with PYP especially exhibiting a higher inhibition ratio than 5‐fluorouracil. With respect to HeLa cells, the different antitumor activities might be related to porphyran molecular weight and solution conformation. Furthermore, the HeLa cell cycle was blocked in the G2/M phase after PYP treatment, leading to cell proliferation inhibition. The induction of cell cycle arrest was related to the changes in the expression of p21, p53, Cyclin B1 and cyclin‐dependent kinase 1. CONCLUSION Pyropia yezoensis porphyran, as applied to medicine and functional food, could potentially be used as a non‐toxic natural adjuvant in cancer therapy. © 2019 Society of Chemical Industry

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Section: Resultsmentioning

confidence: 99%

Section: Ft-ir Analysismentioning

confidence: 99%

Antitumor bioactivity of porphyran extracted from Pyropia yezoensis Chonsoo2 on human cancer cell lines

Yan

et al. 2019

J Sci Food Agric

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“…Compared with the positive control (BHT, IC 50 ¼ 0.11 mg mL À1 ), JHPs still exhibited remarkable ABTS radical scavenging activities. In addition, the ABTS radical scavenging activity of JHP-1 was much higher than that of polysaccharides isolated from commonly consumed tea materials in China, such as Lycium barbarum, 45 dark tea (Qingzhuan brick tea), 46 puerh tea. 47 As shown in Fig.…”

Section: Ft-ir Spectra and Degree Of Esterication Of Jhps From Diffementioning

confidence: 89%

Structural characterization, antioxidant activity, and antiglycation activity of polysaccharides from different chrysanthemum teas

Yuan

Xiang

et al. 2019

RSC Adv.

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“…High antioxidant activity has been observed for extracts of Puerh tea (Huang, Zhang, et al, 2013;Huang, Chen, et al, 2013). TPS from brick tea also exhibited dose-dependent antioxidant activity (Yang et al, 2017), and it was reported that the DPPH radical scavenging activities of TPS could be attributed to the carboxyl group in hexuronic acid (Wang, Chen, et al, 2012;Wang, Yang, et al, 2012). Moreover, Li, Chen, Zhu, and Meng (2017) investigated the antioxidant activity of TPP from three dark tea and found that Ya'an Tibetan tea showed the highest antioxidant activity.…”

Section: Antioxidant Activity Of Tpp and Tps From Tibetan Teamentioning

confidence: 98%

Optimizing synchronous extraction and antioxidant activity evaluation of polyphenols and polysaccharides from Ya'an Tibetan tea (Camellia sinensis)

Zheng

Zhang

et al. 2019

Food Science & Nutrition

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The optimal synchronous conditions to extract tea polysaccharides (TPS) and tea polyphenols (TPP) from Ya'an Tibetan tea were investigated, and the antioxidative capacity of TPS and TPP was measured, and the tea was analyzed to identify the polyphenol compounds it contained. On the basis of single-factor experiments, a Box-Behnken design and response surface methodology were applied to optimize the hot water extraction conditions. The optimal extraction technology was determined as extraction temperature of 83°C, time of 104 min, and liquid-to-material ratio of 41 ml/g, yielding TPP and TPS at 42.70 ± 2.38 mg/g and 53.86 ± 3.79 mg/g, respectively. The TPS and TPP in Ya'an Tibetan tea have high eliminating activities on DPPH and strong reducing power, with TPP showing a higher antioxidant activity than TPS. UHPLC-QqQ-MS/MS analysis identified EGCG, GCG, and ECG as major polyphenol components in Ya'an Tibetan tea. These findings might promote the application of Ya'an Tibetan tea in the food industry. K E Y W O R D Santioxidant activity, optimizing synchronous extraction, tea polyphenols, tea polyphenols compositions, tea polysaccharides, Ya'an Tibetan tea

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Structural characterization and evaluation of the antioxidant activities of polysaccharides extracted from Qingzhuan brick tea

Cited by 110 publications

References 29 publications

Antitumor bioactivity of porphyran extracted from Pyropia yezoensis Chonsoo2 on human cancer cell lines

Antitumor bioactivity of porphyran extracted from Pyropia yezoensis Chonsoo2 on human cancer cell lines

Structural characterization, antioxidant activity, and antiglycation activity of polysaccharides from different chrysanthemum teas

Optimizing synchronous extraction and antioxidant activity evaluation of polyphenols and polysaccharides from Ya'an Tibetan tea (Camellia sinensis)

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