Abstract:The high-sulfated derivative of Ulva pertusa polysaccharide (HU), with unclear structure, has better anti-hyperlipidmia activity than U pertusa polysaccharide ulvan (U). In this study, we explore the main structure of HU and its therapeutic effect against nonalcoholic fatty liver disease (NAFLD). The main structure of HU was elucidated using FT-IR and NMR (13C, 1H, COSY, HSQC, HMBC). The anti-NAFLD activity of HU was explored using the high-fat diet mouse model to detect indicators of blood lipid and liver fun… Show more
“…Our previous investigations have shown that HU synthesized under this condition has good hypolipidemic activity, thus we applied the same methodology for subsequent experiments, including this one. 20,33…”
“…Our previous investigations have shown that HU synthesized under this condition has good hypolipidemic activity, thus we applied the same methodology for subsequent experiments, including this one. 20,33…”
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